Low Incidence of p53 Mutations in Well-differentiated Tongue Squamous Cell Carcinoma in Japan

Background: Despite an increasing number of patients suffering from squamous cell carcinomas of the tongue, little is known about the molecular mechanisms involved in the origin and development of these neoplasms. Methods: We screened microdissected tongue squamous cell carcinoma (TSC) specimens fro...

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Veröffentlicht in:	Japanese journal of clinical oncology 2002-09, Vol.32 (9), p.327-331
Hauptverfasser:	Tsurusako, Shin-Ichi, Tanaka, Hisashi, Hayashi, Yasushi, Tohnai, Iwai, Ueda, Minoru, Ishizaki, Kanji
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Carcinoma, Squamous Cell - genetics Female Genes, p53 - genetics Humans Key words: p53 tumor suppressor gene – tongue cancer – squamous cell carcinoma – well differentiated Male Middle Aged Mutation Polymerase Chain Reaction Polymorphism, Single-Stranded Conformational Tongue Neoplasms - genetics
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