Electrochemical performance, biocompatibility, and adhesion of new polymer matrices for solid-state ion sensors
Ammonium and potassium ion-selective membranes formulated with PVC/hydroxylated PVC, polyurethane/hydroxylated PVC, and moisture-curable silicone rubber matrices are studied in an effort to extend the lifetime of solid-state ion sensors through improved membrane adhesion. The PVC/membranes exhibit e...
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| Veröffentlicht in: | Analytical chemistry (Washington) 1991-09, Vol.63 (17), p.1666-1672 |
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| container_issue | 17 |
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| container_title | Analytical chemistry (Washington) |
| container_volume | 63 |
| creator | GEUN SIG CHA DONG LIU MEYERHOFF, M. E CANTOR, H. C MIDGLEY, A. R GOLDBERG, H. D BROWN, R. B |
| description | Ammonium and potassium ion-selective membranes formulated with PVC/hydroxylated PVC, polyurethane/hydroxylated PVC, and moisture-curable silicone rubber matrices are studied in an effort to extend the lifetime of solid-state ion sensors through improved membrane adhesion. The PVC/membranes exhibit electrochemical performance equivalent to that of conventional PVC membranes in terms of slope, detection limit, and selectivity. The polyurethane- and silicone-rubber-based membranes have better adhesion to silicon nitride than do PVC or hydroxylated PVC matrices. Incorporating a silanizing reagent (silicon tetrachloride) significantly improves the adhesion of the polyurethane matrix. The use of silicon tetrachloride in membrane matrices also enhances the electrochemical stability of the interfacial potential between ion-selective polymer-matrix membranes and silver epoxy inner reference electrodes of solid-state sensors. The biocompatibility of the polymer matrices is examined via radiotracer protein adsorption studies and whole blood clotting time measurements. The polyurethane- and silicone-rubber-based membranes exhibit less overall nonspecific protein adsorption than the PVC or hydroxylated PVC matrices. |
| doi_str_mv | 10.1021/ac00017a003 |
| format | Article |
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The use of silicon tetrachloride in membrane matrices also enhances the electrochemical stability of the interfacial potential between ion-selective polymer-matrix membranes and silver epoxy inner reference electrodes of solid-state sensors. The biocompatibility of the polymer matrices is examined via radiotracer protein adsorption studies and whole blood clotting time measurements. 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Incorporating a silanizing reagent (silicon tetrachloride) significantly improves the adhesion of the polyurethane matrix. The use of silicon tetrachloride in membrane matrices also enhances the electrochemical stability of the interfacial potential between ion-selective polymer-matrix membranes and silver epoxy inner reference electrodes of solid-state sensors. The biocompatibility of the polymer matrices is examined via radiotracer protein adsorption studies and whole blood clotting time measurements. The polyurethane- and silicone-rubber-based membranes exhibit less overall nonspecific protein adsorption than the PVC or hydroxylated PVC matrices.</description><subject>Adhesiveness</subject><subject>Application fields</subject><subject>Applied sciences</subject><subject>Biocompatible Materials</subject><subject>Biosensing Techniques</subject><subject>Electrochemistry</subject><subject>Exact sciences and technology</subject><subject>Humans</subject><subject>In Vitro Techniques</subject><subject>Polymer industry, paints, wood</subject><subject>Polymers</subject><subject>Technology of polymers</subject><issn>0003-2700</issn><issn>1520-6882</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo9kEtLAzEUhYMotVZXroUsxJWjeTTJzFJKfUDBja5LJnPHRpLJmKRI_70RB1f3cM_HWXwIXVJyRwmj99oQQqjShPAjNKeCkUrWNTtG8_LnFVOEnKKzlD4LRQmVMzSjqm6WXM1RWDswOQazA2-NdniE2Ifo9WDgFrc2mOBHnW1rnc2HW6yHDutuB8mGAYceD_CNx-AOHiL2OkdrIOEygFNwtqtS1hnwL5tgSCGmc3TSa5fgYroL9P64fls9V5vXp5fVw6b6YIrmquadXLai0WbZc62UFLyWTQlAoOmYFKVt-pbVfae4UowyzbkAYIXhgrR8gW7-dscYvvaQ8tbbZMA5PUDYp61iUhJR9CzQ1QTuWw_ddozW63jYToZKfz31OhU_fSxmbPrHBC2MEPwH2Ax1QQ</recordid><startdate>19910901</startdate><enddate>19910901</enddate><creator>GEUN SIG CHA</creator><creator>DONG LIU</creator><creator>MEYERHOFF, M. 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B</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Electrochemical performance, biocompatibility, and adhesion of new polymer matrices for solid-state ion sensors</atitle><jtitle>Analytical chemistry (Washington)</jtitle><addtitle>Anal Chem</addtitle><date>1991-09-01</date><risdate>1991</risdate><volume>63</volume><issue>17</issue><spage>1666</spage><epage>1672</epage><pages>1666-1672</pages><issn>0003-2700</issn><eissn>1520-6882</eissn><coden>ANCHAM</coden><abstract>Ammonium and potassium ion-selective membranes formulated with PVC/hydroxylated PVC, polyurethane/hydroxylated PVC, and moisture-curable silicone rubber matrices are studied in an effort to extend the lifetime of solid-state ion sensors through improved membrane adhesion. The PVC/membranes exhibit electrochemical performance equivalent to that of conventional PVC membranes in terms of slope, detection limit, and selectivity. The polyurethane- and silicone-rubber-based membranes have better adhesion to silicon nitride than do PVC or hydroxylated PVC matrices. Incorporating a silanizing reagent (silicon tetrachloride) significantly improves the adhesion of the polyurethane matrix. The use of silicon tetrachloride in membrane matrices also enhances the electrochemical stability of the interfacial potential between ion-selective polymer-matrix membranes and silver epoxy inner reference electrodes of solid-state sensors. The biocompatibility of the polymer matrices is examined via radiotracer protein adsorption studies and whole blood clotting time measurements. The polyurethane- and silicone-rubber-based membranes exhibit less overall nonspecific protein adsorption than the PVC or hydroxylated PVC matrices.</abstract><cop>Washington, DC</cop><pub>American Chemical Society</pub><pmid>1789437</pmid><doi>10.1021/ac00017a003</doi><tpages>7</tpages></addata></record> |
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| ispartof | Analytical chemistry (Washington), 1991-09, Vol.63 (17), p.1666-1672 |
| issn | 0003-2700 1520-6882 |
| language | eng |
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| source | ACS Publications; MEDLINE |
| subjects | Adhesiveness Application fields Applied sciences Biocompatible Materials Biosensing Techniques Electrochemistry Exact sciences and technology Humans In Vitro Techniques Polymer industry, paints, wood Polymers Technology of polymers |
| title | Electrochemical performance, biocompatibility, and adhesion of new polymer matrices for solid-state ion sensors |
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