The Arterial Switch Operation in Transposition of the Great Arteries: Anatomic Indications and Contraindications
Summary 1. The arterial switch procedure is now the operation of choice for typical D-transposition of the great arteries at The Children's Hospital, Boston, USA, the operative mortality rate since 1985 being 3%. 2. There are many anatomic considerations suggesting the morphologically left vent...
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| Veröffentlicht in: | The Thoracic and cardiovascular surgeon 1991-12, Vol.39 (S 2), p.138-150 |
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| creator | Van Praagh, R. Jung, W. K. |
| description | Summary
1. The arterial switch procedure is now the operation of choice for typical D-transposition of the great arteries at The Children's Hospital, Boston, USA, the operative mortality rate since 1985 being 3%.
2. There are many anatomic considerations suggesting the morphologically left ventricle (LV) may well be a better systemic pump than the morphologically right ventricle (RV) which, if true, would favor the arterial switch procedure as opposed to an atrial switch operation:
(1) The LV consists almost entirely of the sinus or pumping portion, and has only a minimal distal infundibular (conal) component. The RV, by contrast, has a relatively much larger infundibular component, the primary function of which is to prevent regurgitation rather than to pump.
(2) Phylogenetically, the LV is the ancient “professional” pump. By contrast, the RV is a comparatively recent modification of the bulbus cordis.
(3) The LV is a two-coronary ventricle, whereas the RV is a one-coronary ventricle.
(4) The LV has relatively much more compact myocardium (stratum compactum) than does the RV.
(5) The mitral valve leaflets are better designed to occlude a circular systemic atrioventricular orifice than are the tricuspid valve leaflets.
(6) The papillary muscles of the LV are large, paired, well balanced, and both arise from the same ventricular wall - the LV free wall. By contrast, the papillary muscles of the RV are comparatively small, numerous, unbalanced, and arise from both ventricular septal and free walls. Hence, dilatation of the LV does not pull the LV papillary muscles apart, whereas dilatation of the RV does pull the RV muscles apart, favoring the development or exacerbation of tricuspid regurgitation.
(7) The LV has two conduciton system radiations, whereas the RV has only one.
3. The current anatomic contraindications to the arterial switch operation in typical D-TGA include the following:
(1) an unprepared LV;
(2) an aortic intramural left coronary artery arising from the right coronary sinus of Valsalva;
(3) pulmonary outflow tract stenosis (with small annulus and subvalvar obstruction) or atresia;
(4) aortic outflow tract stenosis (with small annulus and subvalvar obstruction) with tubular hypoplasia of the aortic arch and preductal coarctation;
(5) tricuspid or mitral atresia;
(6) marked underdevelopment or absence of either the RV sinus or the LV sinus; and
(7) a major anomaly of the systemic and/or pulmonary veins, as in the hetorotaxy syndrome with aspl |
| doi_str_mv | 10.1055/s-2007-1020008 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72659790</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72659790</sourcerecordid><originalsourceid>FETCH-LOGICAL-c423t-c23aa49e0346634b88406531cf17349cd6bf37fb261b0860b7765fa616f6c79b3</originalsourceid><addsrcrecordid>eNp1UM9LwzAYDaLMOb16E3Ly1pk0adJ6G0PnYLCD8xzSNGUZbVKTFPG_t1sHO3l68H7xfQ-AR4zmGGXZS0hShHiC0QAovwJTTEmR4AKl12CKMMcJo2l2C-5COCCEaZ4XEzDBPM9zmk9Bt9truPBReyMb-PljotrDbae9jMZZaCzceWlD54I5Ea6GcUisvJbxnNPhFS6sjK41Cq5tZdQpG6C0FVw6G700F_Ye3NSyCfrhjDPw9f62W34km-1qvVxsEkVTEhOVEilpoRGhjBFaDtcilhGsaswJLVTFyprwukwZLlHOUMk5y2rJMKuZ4kVJZuB57O28--51iKI1QemmkVa7PgiesqzgBRqM89GovAvB61p03rTS_wqMxHFiEcRxYnGeeAg8nZv7stXVxT5uOujJqMe90a0WB9d7O7z6X98fUkyFHQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72659790</pqid></control><display><type>article</type><title>The Arterial Switch Operation in Transposition of the Great Arteries: Anatomic Indications and Contraindications</title><source>MEDLINE</source><source>Thieme Connect Journals</source><creator>Van Praagh, R. ; Jung, W. K.</creator><creatorcontrib>Van Praagh, R. ; Jung, W. K.</creatorcontrib><description>Summary
1. The arterial switch procedure is now the operation of choice for typical D-transposition of the great arteries at The Children's Hospital, Boston, USA, the operative mortality rate since 1985 being 3%.
2. There are many anatomic considerations suggesting the morphologically left ventricle (LV) may well be a better systemic pump than the morphologically right ventricle (RV) which, if true, would favor the arterial switch procedure as opposed to an atrial switch operation:
(1) The LV consists almost entirely of the sinus or pumping portion, and has only a minimal distal infundibular (conal) component. The RV, by contrast, has a relatively much larger infundibular component, the primary function of which is to prevent regurgitation rather than to pump.
(2) Phylogenetically, the LV is the ancient “professional” pump. By contrast, the RV is a comparatively recent modification of the bulbus cordis.
(3) The LV is a two-coronary ventricle, whereas the RV is a one-coronary ventricle.
(4) The LV has relatively much more compact myocardium (stratum compactum) than does the RV.
(5) The mitral valve leaflets are better designed to occlude a circular systemic atrioventricular orifice than are the tricuspid valve leaflets.
(6) The papillary muscles of the LV are large, paired, well balanced, and both arise from the same ventricular wall - the LV free wall. By contrast, the papillary muscles of the RV are comparatively small, numerous, unbalanced, and arise from both ventricular septal and free walls. Hence, dilatation of the LV does not pull the LV papillary muscles apart, whereas dilatation of the RV does pull the RV muscles apart, favoring the development or exacerbation of tricuspid regurgitation.
(7) The LV has two conduciton system radiations, whereas the RV has only one.
3. The current anatomic contraindications to the arterial switch operation in typical D-TGA include the following:
(1) an unprepared LV;
(2) an aortic intramural left coronary artery arising from the right coronary sinus of Valsalva;
(3) pulmonary outflow tract stenosis (with small annulus and subvalvar obstruction) or atresia;
(4) aortic outflow tract stenosis (with small annulus and subvalvar obstruction) with tubular hypoplasia of the aortic arch and preductal coarctation;
(5) tricuspid or mitral atresia;
(6) marked underdevelopment or absence of either the RV sinus or the LV sinus; and
(7) a major anomaly of the systemic and/or pulmonary veins, as in the hetorotaxy syndrome with asplenia. In a series of 193 postmortem cases of D-TGA, the arterial switch procedure appeared to be anatomically feasible (i.e., prohibitive associated anomalies were not present) in 133 cases (69%).
In conclusion, the arterial switch operation is now our procedure of choice in the surgical management of patients with physiologically uncorrected transposition of the great arteries. This paper is primarily concerned with the anatomic indications for, and contraindications to, the ASO.</description><identifier>ISSN: 0171-6425</identifier><identifier>EISSN: 1439-1902</identifier><identifier>DOI: 10.1055/s-2007-1020008</identifier><identifier>PMID: 1788848</identifier><language>eng</language><publisher>Germany</publisher><subject>Animals ; Coronary Vessel Anomalies - surgery ; Heart - anatomy & histology ; Humans ; Infant, Newborn ; Transposition of Great Vessels - surgery ; Ventricular Function - physiology</subject><ispartof>The Thoracic and cardiovascular surgeon, 1991-12, Vol.39 (S 2), p.138-150</ispartof><rights>Georg Thieme Verlag Stuttgart · New York</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c423t-c23aa49e0346634b88406531cf17349cd6bf37fb261b0860b7765fa616f6c79b3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2007-1020008.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><link.rule.ids>315,781,785,3018,3019,27928,27929,54563</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1788848$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Van Praagh, R.</creatorcontrib><creatorcontrib>Jung, W. K.</creatorcontrib><title>The Arterial Switch Operation in Transposition of the Great Arteries: Anatomic Indications and Contraindications</title><title>The Thoracic and cardiovascular surgeon</title><addtitle>Thorac cardiovasc Surg</addtitle><description>Summary
1. The arterial switch procedure is now the operation of choice for typical D-transposition of the great arteries at The Children's Hospital, Boston, USA, the operative mortality rate since 1985 being 3%.
2. There are many anatomic considerations suggesting the morphologically left ventricle (LV) may well be a better systemic pump than the morphologically right ventricle (RV) which, if true, would favor the arterial switch procedure as opposed to an atrial switch operation:
(1) The LV consists almost entirely of the sinus or pumping portion, and has only a minimal distal infundibular (conal) component. The RV, by contrast, has a relatively much larger infundibular component, the primary function of which is to prevent regurgitation rather than to pump.
(2) Phylogenetically, the LV is the ancient “professional” pump. By contrast, the RV is a comparatively recent modification of the bulbus cordis.
(3) The LV is a two-coronary ventricle, whereas the RV is a one-coronary ventricle.
(4) The LV has relatively much more compact myocardium (stratum compactum) than does the RV.
(5) The mitral valve leaflets are better designed to occlude a circular systemic atrioventricular orifice than are the tricuspid valve leaflets.
(6) The papillary muscles of the LV are large, paired, well balanced, and both arise from the same ventricular wall - the LV free wall. By contrast, the papillary muscles of the RV are comparatively small, numerous, unbalanced, and arise from both ventricular septal and free walls. Hence, dilatation of the LV does not pull the LV papillary muscles apart, whereas dilatation of the RV does pull the RV muscles apart, favoring the development or exacerbation of tricuspid regurgitation.
(7) The LV has two conduciton system radiations, whereas the RV has only one.
3. The current anatomic contraindications to the arterial switch operation in typical D-TGA include the following:
(1) an unprepared LV;
(2) an aortic intramural left coronary artery arising from the right coronary sinus of Valsalva;
(3) pulmonary outflow tract stenosis (with small annulus and subvalvar obstruction) or atresia;
(4) aortic outflow tract stenosis (with small annulus and subvalvar obstruction) with tubular hypoplasia of the aortic arch and preductal coarctation;
(5) tricuspid or mitral atresia;
(6) marked underdevelopment or absence of either the RV sinus or the LV sinus; and
(7) a major anomaly of the systemic and/or pulmonary veins, as in the hetorotaxy syndrome with asplenia. In a series of 193 postmortem cases of D-TGA, the arterial switch procedure appeared to be anatomically feasible (i.e., prohibitive associated anomalies were not present) in 133 cases (69%).
In conclusion, the arterial switch operation is now our procedure of choice in the surgical management of patients with physiologically uncorrected transposition of the great arteries. This paper is primarily concerned with the anatomic indications for, and contraindications to, the ASO.</description><subject>Animals</subject><subject>Coronary Vessel Anomalies - surgery</subject><subject>Heart - anatomy & histology</subject><subject>Humans</subject><subject>Infant, Newborn</subject><subject>Transposition of Great Vessels - surgery</subject><subject>Ventricular Function - physiology</subject><issn>0171-6425</issn><issn>1439-1902</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1UM9LwzAYDaLMOb16E3Ly1pk0adJ6G0PnYLCD8xzSNGUZbVKTFPG_t1sHO3l68H7xfQ-AR4zmGGXZS0hShHiC0QAovwJTTEmR4AKl12CKMMcJo2l2C-5COCCEaZ4XEzDBPM9zmk9Bt9truPBReyMb-PljotrDbae9jMZZaCzceWlD54I5Ea6GcUisvJbxnNPhFS6sjK41Cq5tZdQpG6C0FVw6G700F_Ye3NSyCfrhjDPw9f62W34km-1qvVxsEkVTEhOVEilpoRGhjBFaDtcilhGsaswJLVTFyprwukwZLlHOUMk5y2rJMKuZ4kVJZuB57O28--51iKI1QemmkVa7PgiesqzgBRqM89GovAvB61p03rTS_wqMxHFiEcRxYnGeeAg8nZv7stXVxT5uOujJqMe90a0WB9d7O7z6X98fUkyFHQ</recordid><startdate>19911201</startdate><enddate>19911201</enddate><creator>Van Praagh, R.</creator><creator>Jung, W. K.</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19911201</creationdate><title>The Arterial Switch Operation in Transposition of the Great Arteries: Anatomic Indications and Contraindications</title><author>Van Praagh, R. ; Jung, W. K.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c423t-c23aa49e0346634b88406531cf17349cd6bf37fb261b0860b7765fa616f6c79b3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Animals</topic><topic>Coronary Vessel Anomalies - surgery</topic><topic>Heart - anatomy & histology</topic><topic>Humans</topic><topic>Infant, Newborn</topic><topic>Transposition of Great Vessels - surgery</topic><topic>Ventricular Function - physiology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Van Praagh, R.</creatorcontrib><creatorcontrib>Jung, W. K.</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>The Thoracic and cardiovascular surgeon</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Van Praagh, R.</au><au>Jung, W. K.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Arterial Switch Operation in Transposition of the Great Arteries: Anatomic Indications and Contraindications</atitle><jtitle>The Thoracic and cardiovascular surgeon</jtitle><addtitle>Thorac cardiovasc Surg</addtitle><date>1991-12-01</date><risdate>1991</risdate><volume>39</volume><issue>S 2</issue><spage>138</spage><epage>150</epage><pages>138-150</pages><issn>0171-6425</issn><eissn>1439-1902</eissn><abstract>Summary
1. The arterial switch procedure is now the operation of choice for typical D-transposition of the great arteries at The Children's Hospital, Boston, USA, the operative mortality rate since 1985 being 3%.
2. There are many anatomic considerations suggesting the morphologically left ventricle (LV) may well be a better systemic pump than the morphologically right ventricle (RV) which, if true, would favor the arterial switch procedure as opposed to an atrial switch operation:
(1) The LV consists almost entirely of the sinus or pumping portion, and has only a minimal distal infundibular (conal) component. The RV, by contrast, has a relatively much larger infundibular component, the primary function of which is to prevent regurgitation rather than to pump.
(2) Phylogenetically, the LV is the ancient “professional” pump. By contrast, the RV is a comparatively recent modification of the bulbus cordis.
(3) The LV is a two-coronary ventricle, whereas the RV is a one-coronary ventricle.
(4) The LV has relatively much more compact myocardium (stratum compactum) than does the RV.
(5) The mitral valve leaflets are better designed to occlude a circular systemic atrioventricular orifice than are the tricuspid valve leaflets.
(6) The papillary muscles of the LV are large, paired, well balanced, and both arise from the same ventricular wall - the LV free wall. By contrast, the papillary muscles of the RV are comparatively small, numerous, unbalanced, and arise from both ventricular septal and free walls. Hence, dilatation of the LV does not pull the LV papillary muscles apart, whereas dilatation of the RV does pull the RV muscles apart, favoring the development or exacerbation of tricuspid regurgitation.
(7) The LV has two conduciton system radiations, whereas the RV has only one.
3. The current anatomic contraindications to the arterial switch operation in typical D-TGA include the following:
(1) an unprepared LV;
(2) an aortic intramural left coronary artery arising from the right coronary sinus of Valsalva;
(3) pulmonary outflow tract stenosis (with small annulus and subvalvar obstruction) or atresia;
(4) aortic outflow tract stenosis (with small annulus and subvalvar obstruction) with tubular hypoplasia of the aortic arch and preductal coarctation;
(5) tricuspid or mitral atresia;
(6) marked underdevelopment or absence of either the RV sinus or the LV sinus; and
(7) a major anomaly of the systemic and/or pulmonary veins, as in the hetorotaxy syndrome with asplenia. In a series of 193 postmortem cases of D-TGA, the arterial switch procedure appeared to be anatomically feasible (i.e., prohibitive associated anomalies were not present) in 133 cases (69%).
In conclusion, the arterial switch operation is now our procedure of choice in the surgical management of patients with physiologically uncorrected transposition of the great arteries. This paper is primarily concerned with the anatomic indications for, and contraindications to, the ASO.</abstract><cop>Germany</cop><pmid>1788848</pmid><doi>10.1055/s-2007-1020008</doi><tpages>13</tpages></addata></record> |
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| identifier | ISSN: 0171-6425 |
| ispartof | The Thoracic and cardiovascular surgeon, 1991-12, Vol.39 (S 2), p.138-150 |
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| source | MEDLINE; Thieme Connect Journals |
| subjects | Animals Coronary Vessel Anomalies - surgery Heart - anatomy & histology Humans Infant, Newborn Transposition of Great Vessels - surgery Ventricular Function - physiology |
| title | The Arterial Switch Operation in Transposition of the Great Arteries: Anatomic Indications and Contraindications |
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