Stimulation of Cell Surface Plasminogen Activation by Heparin and Related Polyionic Substances

The functional operation of the cell surface pro-u-PA and plasminogen activating system has previously been shown to depend on the assembly of u-PA receptors, plasminogen binding sites, and their respective ligands at the focal adhesions of cell extensions. We now show that additional factors operat...

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Veröffentlicht in:	Seminars in thrombosis and hemostasis 1991-07, Vol.17 (3), p.201-209
Hauptverfasser:	Stephens, Ross W., Pöllänen, Jari, Tapiovaara, Hannele, Woodrow, Graeme, Vaheri, Antti
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cell structures and functions Fibrinolysin - metabolism Fundamental and applied biological sciences. Psychology Heparin - pharmacology Humans Membrane Proteins - drug effects Membrane Proteins - metabolism Molecular and cellular biology Protamines - pharmacology Protein Binding Tumor Cells, Cultured Urokinase-Type Plasminogen Activator - drug effects Urokinase-Type Plasminogen Activator - metabolism
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