Imaging of systemic Candida albicans infections with a radioiodinated monoclonal antibody: Experimental study in the guinea pig

Guinea pigs intravenously infected with Candida albicans were scanned to evaluate the use of radioiodinated monoclonal antibodies (MAb) to fungal antigens for detecting tissue infection sites. A total of 18 infected and 8 uninfected animals were used. MAb and F(ab′) 2 fragments directed against cell...

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Veröffentlicht in:	International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology Nuclear medicine and biology, 1991, Vol.18 (7), p.677-686
Hauptverfasser:	Poulain, Daniel, Deveaux, Marc, Cailliez, Jean-Charles, Hossein-Foucher, Claude, Dutoit, Emmanuel, Camus, Daniel, Van Cutsem, Jan, Marchandise, Xavier
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibodies, Monoclonal Antigens, Fungal - immunology Biological and medical sciences Candida albicans - immunology Candidiasis - complications Candidiasis - diagnostic imaging Candidiasis - microbiology Guinea Pigs Humans Immunoglobulin Fab Fragments - immunology Iodine Radioisotopes Male Medical sciences Radioimmunodetection - methods Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Online-Zugang:	Volltext
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