Semliki Forest virus infection is enhanced in Th1-prone SJL mice but not in Th2-prone BALB/c mice during Linomide-induced immunomodulation

Linomide (quinoline-3-carboxamide) is an immunomodulator with diverse effects on the immune system. Its beneficial effects on experimental autoimmune disease models have been linked to downregulation of Th1 cytokines and altered macrophage functions. We studied this effect of downregulation of Th1-t...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of neuroimmunology 2002-11, Vol.132 (1), p.83-92
Hauptverfasser:	Peltoniemi, J, Setälä, N, Broberg, E, Röyttä, M, Hukkanen, V, Salmi, A.A, Erälinna, J.-P
Format:	Artikel
Sprache:	eng
Schlagworte:	Adjuvants, Immunologic - pharmacology Alphavirus Infections - immunology Animals Antigen-presenting cells Antigen-Presenting Cells - drug effects Brain - virology CD11b Antigen - analysis Cytokines Encephalomyelitis, Autoimmune, Experimental - immunology Hydroxyquinolines - pharmacology Immunomodulation Infection Interferon-gamma - biosynthesis Interleukin-12 - biosynthesis Mice Mice, Inbred BALB C RNA, Viral - analysis Semliki Forest virus Spleen - cytology Th1 Cells - immunology Th2 Cells - immunology Viral Load
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!