Pick's disease: α- and β-synuclein-immunoreactive Pick bodies in the dentate gyrus

Recent studies have shown that neurofibrillary tangles frequently coexist with alpha-synuclein (alpha-S)-positive fibrillary inclusions in the limbic system in Alzheimer's disease. To elucidate whether alpha-, beta- and gamma-S immunoreactivity is present in Pick bodies (PBs), we examined immun...

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Veröffentlicht in:	Acta neuropathologica 2002-11, Vol.104 (5), p.455-461
Hauptverfasser:	MORI, Fumiaki, HAYASHI, Shintaro, YAMAGISHI, Shin-Ichiro, YOSHIMOTO, Makoto, YAGIHASHI, Soroku, TAKAHASHI, Hitoshi, WAKABAYASHI, Koichi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged alpha-Synuclein beta-Synuclein Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dentate Gyrus - metabolism Dentate Gyrus - ultrastructure Humans Immunohistochemistry Medical sciences Microscopy, Immunoelectron Middle Aged Nerve Tissue Proteins - metabolism Neurology Phosphorylation Pick Disease of the Brain - metabolism Synucleins tau Proteins - biosynthesis
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