Lewis Base Activation of Lewis Acids. Addition of Silyl Ketene Acetals to Aldehydes

The weak Lewis acid silicon tetrachloride can be activated by catalytic amounts of the chiral bisphosphoramide (R,R)-3 to form a highly reactive, chiral trichlorosilyl cation which is an extremely effective promoter of aldol addition reactions between aldehydes and silyl ketene acetals. The tert-but...

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Veröffentlicht in:	Journal of the American Chemical Society 2002-11, Vol.124 (45), p.13405-13407
Hauptverfasser:	Denmark, Scott E, Wynn, Thomas, Beutner, Gregory L
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Exact sciences and technology Organic chemistry
Online-Zugang:	Volltext
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