Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma
Melanoma is an aggressive malignancy with a growing prevalence. Although early detection and excision offer a potential cure, recurrences and metastases are not uncommon. Fine‐needle aspiration (FNA) can play a vital role in their detection as a relatively noninvasive, rapid, and economical alternat...
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Veröffentlicht in: | Diagnostic cytopathology 2002-11, Vol.27 (5), p.286-290 |
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description | Melanoma is an aggressive malignancy with a growing prevalence. Although early detection and excision offer a potential cure, recurrences and metastases are not uncommon. Fine‐needle aspiration (FNA) can play a vital role in their detection as a relatively noninvasive, rapid, and economical alternative for tracking disease evolution. Prior clinical history and classic cytological features of melanoma (loosely cohesive smear pattern and single cells with large nuclei, prominent nucleoli, and melanin pigment) aid in cytological diagnoses. However, not all melanomas contain melanin pigment or characteristic cytologic features. We examined a large series of melanoma cases to determine the incidence of melanin pigment, the most common cell morphology, and the presence or absence of apoptosis/necrosis associated with this highly aggressive neoplasm. Diagn. Cytopathol. 2002;27:286–290. © 2002 Wiley‐Liss, Inc. |
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Although early detection and excision offer a potential cure, recurrences and metastases are not uncommon. Fine‐needle aspiration (FNA) can play a vital role in their detection as a relatively noninvasive, rapid, and economical alternative for tracking disease evolution. Prior clinical history and classic cytological features of melanoma (loosely cohesive smear pattern and single cells with large nuclei, prominent nucleoli, and melanin pigment) aid in cytological diagnoses. However, not all melanomas contain melanin pigment or characteristic cytologic features. We examined a large series of melanoma cases to determine the incidence of melanin pigment, the most common cell morphology, and the presence or absence of apoptosis/necrosis associated with this highly aggressive neoplasm. Diagn. 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Cytopathol</addtitle><description>Melanoma is an aggressive malignancy with a growing prevalence. Although early detection and excision offer a potential cure, recurrences and metastases are not uncommon. Fine‐needle aspiration (FNA) can play a vital role in their detection as a relatively noninvasive, rapid, and economical alternative for tracking disease evolution. Prior clinical history and classic cytological features of melanoma (loosely cohesive smear pattern and single cells with large nuclei, prominent nucleoli, and melanin pigment) aid in cytological diagnoses. However, not all melanomas contain melanin pigment or characteristic cytologic features. We examined a large series of melanoma cases to determine the incidence of melanin pigment, the most common cell morphology, and the presence or absence of apoptosis/necrosis associated with this highly aggressive neoplasm. Diagn. Cytopathol. 2002;27:286–290. © 2002 Wiley‐Liss, Inc.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Biopsy, Needle</subject><subject>Cell Death</subject><subject>cytology</subject><subject>Dermatology</subject><subject>Female</subject><subject>fine-needle aspiration</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Inclusion Bodies - metabolism</subject><subject>Male</subject><subject>Medical sciences</subject><subject>melanin pigment</subject><subject>Melanins - metabolism</subject><subject>melanoma</subject><subject>Melanoma - metabolism</subject><subject>Melanoma - pathology</subject><subject>Middle Aged</subject><subject>Neoplasm Metastasis - pathology</subject><subject>Neoplasm Recurrence, Local - metabolism</subject><subject>Neoplasm Recurrence, Local - pathology</subject><subject>Retrospective Studies</subject><subject>Tumors of the skin and soft tissue. Premalignant lesions</subject><issn>8755-1039</issn><issn>1097-0339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10E1v1DAQBmALUdGlVOIXoFxAXEL9neSIllIq2oIQVaterIkzBkMSb-1EsP8etxvoidNoNI9mRi8hzxl9wyjlR53NlTXyEVkx2lQlFaJ5TFZ1pVTJqGj2ydOUflBKG870E7LPuGSsaeSKXK23UxhC3HwPffjmbeEQpjliKoIrnB-xHBG7HgtIGx9h8mG8mww4QZpyawsYuyKinWPEccqDHsYwwDOy56BPeLjUA3L5_vjr-kN59unkdP32rLSiVrKUOr8hWs5lRWWrWQfaSuts3YJknEolQFW1VFI6px3lNeq2ql1LRWehdUockFe7vZsYbmdMkxl8stjnLzDMyVRcK661zPD1DtoYUorozCb6AeLWMGruQjSdNfchZvpi2Tm3A3YPcEktg5cLgGShdxFG69ODk0IzrXV25c798j1u_3vQvFv_Pbx4nyb8_c9D_Gl0JSplri5OzHX9pf74-ZybG_EHRmGWyg</recordid><startdate>200211</startdate><enddate>200211</enddate><creator>Saqi, Anjali</creator><creator>McGrath, Cindy M.</creator><creator>Skovronsky, Daniel</creator><creator>Yu, Gordon H.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200211</creationdate><title>Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma</title><author>Saqi, Anjali ; McGrath, Cindy M. ; Skovronsky, Daniel ; Yu, Gordon H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3854-461993b224704b61da6c4cfc8ba4120453a5784544ff6f028e6b78fb03dcabf53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Biopsy, Needle</topic><topic>Cell Death</topic><topic>cytology</topic><topic>Dermatology</topic><topic>Female</topic><topic>fine-needle aspiration</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Inclusion Bodies - metabolism</topic><topic>Male</topic><topic>Medical sciences</topic><topic>melanin pigment</topic><topic>Melanins - metabolism</topic><topic>melanoma</topic><topic>Melanoma - metabolism</topic><topic>Melanoma - pathology</topic><topic>Middle Aged</topic><topic>Neoplasm Metastasis - pathology</topic><topic>Neoplasm Recurrence, Local - metabolism</topic><topic>Neoplasm Recurrence, Local - pathology</topic><topic>Retrospective Studies</topic><topic>Tumors of the skin and soft tissue. Premalignant lesions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saqi, Anjali</creatorcontrib><creatorcontrib>McGrath, Cindy M.</creatorcontrib><creatorcontrib>Skovronsky, Daniel</creatorcontrib><creatorcontrib>Yu, Gordon H.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Diagnostic cytopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saqi, Anjali</au><au>McGrath, Cindy M.</au><au>Skovronsky, Daniel</au><au>Yu, Gordon H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma</atitle><jtitle>Diagnostic cytopathology</jtitle><addtitle>Diagn. 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subjects | Adult Aged Aged, 80 and over Biological and medical sciences Biopsy, Needle Cell Death cytology Dermatology Female fine-needle aspiration Humans Immunohistochemistry Inclusion Bodies - metabolism Male Medical sciences melanin pigment Melanins - metabolism melanoma Melanoma - metabolism Melanoma - pathology Middle Aged Neoplasm Metastasis - pathology Neoplasm Recurrence, Local - metabolism Neoplasm Recurrence, Local - pathology Retrospective Studies Tumors of the skin and soft tissue. Premalignant lesions |
title | Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma |
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