Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma

Melanoma is an aggressive malignancy with a growing prevalence. Although early detection and excision offer a potential cure, recurrences and metastases are not uncommon. Fine‐needle aspiration (FNA) can play a vital role in their detection as a relatively noninvasive, rapid, and economical alternat...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Diagnostic cytopathology 2002-11, Vol.27 (5), p.286-290
Hauptverfasser: Saqi, Anjali, McGrath, Cindy M., Skovronsky, Daniel, Yu, Gordon H.
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 290
container_issue 5
container_start_page 286
container_title Diagnostic cytopathology
container_volume 27
creator Saqi, Anjali
McGrath, Cindy M.
Skovronsky, Daniel
Yu, Gordon H.
description Melanoma is an aggressive malignancy with a growing prevalence. Although early detection and excision offer a potential cure, recurrences and metastases are not uncommon. Fine‐needle aspiration (FNA) can play a vital role in their detection as a relatively noninvasive, rapid, and economical alternative for tracking disease evolution. Prior clinical history and classic cytological features of melanoma (loosely cohesive smear pattern and single cells with large nuclei, prominent nucleoli, and melanin pigment) aid in cytological diagnoses. However, not all melanomas contain melanin pigment or characteristic cytologic features. We examined a large series of melanoma cases to determine the incidence of melanin pigment, the most common cell morphology, and the presence or absence of apoptosis/necrosis associated with this highly aggressive neoplasm. Diagn. Cytopathol. 2002;27:286–290. © 2002 Wiley‐Liss, Inc.
doi_str_mv 10.1002/dc.10194
format Article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_72652664</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>72652664</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3854-461993b224704b61da6c4cfc8ba4120453a5784544ff6f028e6b78fb03dcabf53</originalsourceid><addsrcrecordid>eNp10E1v1DAQBmALUdGlVOIXoFxAXEL9neSIllIq2oIQVaterIkzBkMSb-1EsP8etxvoidNoNI9mRi8hzxl9wyjlR53NlTXyEVkx2lQlFaJ5TFZ1pVTJqGj2ydOUflBKG870E7LPuGSsaeSKXK23UxhC3HwPffjmbeEQpjliKoIrnB-xHBG7HgtIGx9h8mG8mww4QZpyawsYuyKinWPEccqDHsYwwDOy56BPeLjUA3L5_vjr-kN59unkdP32rLSiVrKUOr8hWs5lRWWrWQfaSuts3YJknEolQFW1VFI6px3lNeq2ql1LRWehdUockFe7vZsYbmdMkxl8stjnLzDMyVRcK661zPD1DtoYUorozCb6AeLWMGruQjSdNfchZvpi2Tm3A3YPcEktg5cLgGShdxFG69ODk0IzrXV25c798j1u_3vQvFv_Pbx4nyb8_c9D_Gl0JSplri5OzHX9pf74-ZybG_EHRmGWyg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>72652664</pqid></control><display><type>article</type><title>Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma</title><source>MEDLINE</source><source>Wiley Online Library All Journals</source><creator>Saqi, Anjali ; McGrath, Cindy M. ; Skovronsky, Daniel ; Yu, Gordon H.</creator><creatorcontrib>Saqi, Anjali ; McGrath, Cindy M. ; Skovronsky, Daniel ; Yu, Gordon H.</creatorcontrib><description>Melanoma is an aggressive malignancy with a growing prevalence. Although early detection and excision offer a potential cure, recurrences and metastases are not uncommon. Fine‐needle aspiration (FNA) can play a vital role in their detection as a relatively noninvasive, rapid, and economical alternative for tracking disease evolution. Prior clinical history and classic cytological features of melanoma (loosely cohesive smear pattern and single cells with large nuclei, prominent nucleoli, and melanin pigment) aid in cytological diagnoses. However, not all melanomas contain melanin pigment or characteristic cytologic features. We examined a large series of melanoma cases to determine the incidence of melanin pigment, the most common cell morphology, and the presence or absence of apoptosis/necrosis associated with this highly aggressive neoplasm. Diagn. Cytopathol. 2002;27:286–290. © 2002 Wiley‐Liss, Inc.</description><identifier>ISSN: 8755-1039</identifier><identifier>EISSN: 1097-0339</identifier><identifier>DOI: 10.1002/dc.10194</identifier><identifier>PMID: 12411994</identifier><identifier>CODEN: DICYE7</identifier><language>eng</language><publisher>New York: Wiley Subscription Services, Inc., A Wiley Company</publisher><subject>Adult ; Aged ; Aged, 80 and over ; Biological and medical sciences ; Biopsy, Needle ; Cell Death ; cytology ; Dermatology ; Female ; fine-needle aspiration ; Humans ; Immunohistochemistry ; Inclusion Bodies - metabolism ; Male ; Medical sciences ; melanin pigment ; Melanins - metabolism ; melanoma ; Melanoma - metabolism ; Melanoma - pathology ; Middle Aged ; Neoplasm Metastasis - pathology ; Neoplasm Recurrence, Local - metabolism ; Neoplasm Recurrence, Local - pathology ; Retrospective Studies ; Tumors of the skin and soft tissue. Premalignant lesions</subject><ispartof>Diagnostic cytopathology, 2002-11, Vol.27 (5), p.286-290</ispartof><rights>Copyright © 2002 Wiley‐Liss, Inc.</rights><rights>2003 INIST-CNRS</rights><rights>Copyright 2002 Wiley-Liss, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3854-461993b224704b61da6c4cfc8ba4120453a5784544ff6f028e6b78fb03dcabf53</citedby><cites>FETCH-LOGICAL-c3854-461993b224704b61da6c4cfc8ba4120453a5784544ff6f028e6b78fb03dcabf53</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1002%2Fdc.10194$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1002%2Fdc.10194$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,780,784,1416,27923,27924,45573,45574</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=14361666$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/12411994$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Saqi, Anjali</creatorcontrib><creatorcontrib>McGrath, Cindy M.</creatorcontrib><creatorcontrib>Skovronsky, Daniel</creatorcontrib><creatorcontrib>Yu, Gordon H.</creatorcontrib><title>Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma</title><title>Diagnostic cytopathology</title><addtitle>Diagn. Cytopathol</addtitle><description>Melanoma is an aggressive malignancy with a growing prevalence. Although early detection and excision offer a potential cure, recurrences and metastases are not uncommon. Fine‐needle aspiration (FNA) can play a vital role in their detection as a relatively noninvasive, rapid, and economical alternative for tracking disease evolution. Prior clinical history and classic cytological features of melanoma (loosely cohesive smear pattern and single cells with large nuclei, prominent nucleoli, and melanin pigment) aid in cytological diagnoses. However, not all melanomas contain melanin pigment or characteristic cytologic features. We examined a large series of melanoma cases to determine the incidence of melanin pigment, the most common cell morphology, and the presence or absence of apoptosis/necrosis associated with this highly aggressive neoplasm. Diagn. Cytopathol. 2002;27:286–290. © 2002 Wiley‐Liss, Inc.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Biopsy, Needle</subject><subject>Cell Death</subject><subject>cytology</subject><subject>Dermatology</subject><subject>Female</subject><subject>fine-needle aspiration</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Inclusion Bodies - metabolism</subject><subject>Male</subject><subject>Medical sciences</subject><subject>melanin pigment</subject><subject>Melanins - metabolism</subject><subject>melanoma</subject><subject>Melanoma - metabolism</subject><subject>Melanoma - pathology</subject><subject>Middle Aged</subject><subject>Neoplasm Metastasis - pathology</subject><subject>Neoplasm Recurrence, Local - metabolism</subject><subject>Neoplasm Recurrence, Local - pathology</subject><subject>Retrospective Studies</subject><subject>Tumors of the skin and soft tissue. Premalignant lesions</subject><issn>8755-1039</issn><issn>1097-0339</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp10E1v1DAQBmALUdGlVOIXoFxAXEL9neSIllIq2oIQVaterIkzBkMSb-1EsP8etxvoidNoNI9mRi8hzxl9wyjlR53NlTXyEVkx2lQlFaJ5TFZ1pVTJqGj2ydOUflBKG870E7LPuGSsaeSKXK23UxhC3HwPffjmbeEQpjliKoIrnB-xHBG7HgtIGx9h8mG8mww4QZpyawsYuyKinWPEccqDHsYwwDOy56BPeLjUA3L5_vjr-kN59unkdP32rLSiVrKUOr8hWs5lRWWrWQfaSuts3YJknEolQFW1VFI6px3lNeq2ql1LRWehdUockFe7vZsYbmdMkxl8stjnLzDMyVRcK661zPD1DtoYUorozCb6AeLWMGruQjSdNfchZvpi2Tm3A3YPcEktg5cLgGShdxFG69ODk0IzrXV25c798j1u_3vQvFv_Pbx4nyb8_c9D_Gl0JSplri5OzHX9pf74-ZybG_EHRmGWyg</recordid><startdate>200211</startdate><enddate>200211</enddate><creator>Saqi, Anjali</creator><creator>McGrath, Cindy M.</creator><creator>Skovronsky, Daniel</creator><creator>Yu, Gordon H.</creator><general>Wiley Subscription Services, Inc., A Wiley Company</general><general>Wiley-Liss</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200211</creationdate><title>Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma</title><author>Saqi, Anjali ; McGrath, Cindy M. ; Skovronsky, Daniel ; Yu, Gordon H.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3854-461993b224704b61da6c4cfc8ba4120453a5784544ff6f028e6b78fb03dcabf53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Biopsy, Needle</topic><topic>Cell Death</topic><topic>cytology</topic><topic>Dermatology</topic><topic>Female</topic><topic>fine-needle aspiration</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Inclusion Bodies - metabolism</topic><topic>Male</topic><topic>Medical sciences</topic><topic>melanin pigment</topic><topic>Melanins - metabolism</topic><topic>melanoma</topic><topic>Melanoma - metabolism</topic><topic>Melanoma - pathology</topic><topic>Middle Aged</topic><topic>Neoplasm Metastasis - pathology</topic><topic>Neoplasm Recurrence, Local - metabolism</topic><topic>Neoplasm Recurrence, Local - pathology</topic><topic>Retrospective Studies</topic><topic>Tumors of the skin and soft tissue. Premalignant lesions</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Saqi, Anjali</creatorcontrib><creatorcontrib>McGrath, Cindy M.</creatorcontrib><creatorcontrib>Skovronsky, Daniel</creatorcontrib><creatorcontrib>Yu, Gordon H.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Diagnostic cytopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Saqi, Anjali</au><au>McGrath, Cindy M.</au><au>Skovronsky, Daniel</au><au>Yu, Gordon H.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma</atitle><jtitle>Diagnostic cytopathology</jtitle><addtitle>Diagn. Cytopathol</addtitle><date>2002-11</date><risdate>2002</risdate><volume>27</volume><issue>5</issue><spage>286</spage><epage>290</epage><pages>286-290</pages><issn>8755-1039</issn><eissn>1097-0339</eissn><coden>DICYE7</coden><abstract>Melanoma is an aggressive malignancy with a growing prevalence. Although early detection and excision offer a potential cure, recurrences and metastases are not uncommon. Fine‐needle aspiration (FNA) can play a vital role in their detection as a relatively noninvasive, rapid, and economical alternative for tracking disease evolution. Prior clinical history and classic cytological features of melanoma (loosely cohesive smear pattern and single cells with large nuclei, prominent nucleoli, and melanin pigment) aid in cytological diagnoses. However, not all melanomas contain melanin pigment or characteristic cytologic features. We examined a large series of melanoma cases to determine the incidence of melanin pigment, the most common cell morphology, and the presence or absence of apoptosis/necrosis associated with this highly aggressive neoplasm. Diagn. Cytopathol. 2002;27:286–290. © 2002 Wiley‐Liss, Inc.</abstract><cop>New York</cop><pub>Wiley Subscription Services, Inc., A Wiley Company</pub><pmid>12411994</pmid><doi>10.1002/dc.10194</doi><tpages>5</tpages></addata></record>
fulltext fulltext
identifier ISSN: 8755-1039
ispartof Diagnostic cytopathology, 2002-11, Vol.27 (5), p.286-290
issn 8755-1039
1097-0339
language eng
recordid cdi_proquest_miscellaneous_72652664
source MEDLINE; Wiley Online Library All Journals
subjects Adult
Aged
Aged, 80 and over
Biological and medical sciences
Biopsy, Needle
Cell Death
cytology
Dermatology
Female
fine-needle aspiration
Humans
Immunohistochemistry
Inclusion Bodies - metabolism
Male
Medical sciences
melanin pigment
Melanins - metabolism
melanoma
Melanoma - metabolism
Melanoma - pathology
Middle Aged
Neoplasm Metastasis - pathology
Neoplasm Recurrence, Local - metabolism
Neoplasm Recurrence, Local - pathology
Retrospective Studies
Tumors of the skin and soft tissue. Premalignant lesions
title Cytomorphologic features of fine-needle aspiration of metastatic and recurrent melanoma
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-13T04%3A54%3A57IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Cytomorphologic%20features%20of%20fine-needle%20aspiration%20of%20metastatic%20and%20recurrent%20melanoma&rft.jtitle=Diagnostic%20cytopathology&rft.au=Saqi,%20Anjali&rft.date=2002-11&rft.volume=27&rft.issue=5&rft.spage=286&rft.epage=290&rft.pages=286-290&rft.issn=8755-1039&rft.eissn=1097-0339&rft.coden=DICYE7&rft_id=info:doi/10.1002/dc.10194&rft_dat=%3Cproquest_cross%3E72652664%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=72652664&rft_id=info:pmid/12411994&rfr_iscdi=true