Sustained molecular remission in a patient with CML in blastic crisis receiving dose‐reduced hematopoietic stem‐cell transplantation followed by early withdrawal of cyclosporine and prophylactic use of interferon‐α

A 54‐year‐old man with chronic myelocytic leukemia in blastic phase received reduced‐intensity transplantation (RIST) from an HLA‐identical unrelated donor. The preparative regimen consisted of busulfan, fludarabine, and anti‐thymocyte globulin. Graft‐versus‐host disease (GVHD) prophylaxis was cyclo...

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Veröffentlicht in:	American journal of hematology 2002-11, Vol.71 (3), p.196-199
Hauptverfasser:	Hamaki, Tamae, Kami, Masahiro, Momomura, Shin‐ichi, Mineishi, Shin, Kusumi, Eiji, Kanda, Yoshinobu, Ueyama, Jun‐ichi, Miyakoshi, Shigesaburo, Morinaga, Shin‐ichi, Takaue, Yoichi, Mutou, Yoshitomo
Format:	Artikel
Sprache:	eng
Schlagworte:	Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blast Crisis - surgery Bone marrow, stem cells transplantation. Graft versus host reaction chronic myelocytic leukemia cyclosporine Cyclosporine - administration & dosage Cyclosporine - therapeutic use Drug Administration Schedule Graft vs Host Disease - physiopathology Graft vs Host Disease - prevention & control Hematopoietic Stem Cell Transplantation - methods Humans Immunosuppressive Agents - administration & dosage Immunosuppressive Agents - therapeutic use Interferon-alpha - therapeutic use interferon‐α Leukemia, Myelogenous, Chronic, BCR-ABL Positive - drug therapy Leukemia, Myelogenous, Chronic, BCR-ABL Positive - pathology Leukemia, Myelogenous, Chronic, BCR-ABL Positive - surgery Male Medical sciences Middle Aged Neoplasm Recurrence, Local - prevention & control reduced‐intensity hematopoietic stem‐cell transplantation Remission Induction Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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