DNA Pooling: a tool for large-scale association studies

Key Points DNA pooling is an effective way of reducing the cost of genotyping in large-scale association studies. DNA pools should be constituted with care to ensure that equal amounts of DNA are contributed by the individuals that make up a pool. Accurate quantitative genotyping assays are availabl...

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Veröffentlicht in:	Nature reviews. Genetics 2002-11, Vol.3 (11), p.862-871
Hauptverfasser:	Sham, Pak, Bader, Joel S., Craig, Ian, O'Donovan, Michael, Owen, Michael
Format:	Artikel
Sprache:	eng
Schlagworte:	Agriculture Animal Genetics and Genomics Animals Automation Biomedical and Life Sciences Biomedicine Cancer Research DNA Gene Frequency Gene Function Genetic Techniques Genetic testing Genomes Haplotypes Human Genetics Humans Mutation Polymerase Chain Reaction Polymorphism, Single Nucleotide review-article Spectrum analysis
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