The role of endogenous dopamine in the hypermotility response to intra-accumbens AMPA

The present study was designed to investigate the role of dopamine in the locomotor stimulant response produced by the bilateral administration of α-amino-3-hydroxy-5-methylisoxazole-4-proprionic acid (AMPA) into the nucleus accumbens. The hypermotility produced by lower doses of AMPA (up to 0.25 μg...

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Veröffentlicht in:	Brain research 1991-09, Vol.559 (1), p.100-108
Hauptverfasser:	Boldry, Robert C., Willins, David L., Wallace, Lane J., Uretsky, Norman J.
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid alpha-Methyltyrosine Amphetamine - pharmacology Animals Benzazepines - pharmacology Biological and medical sciences Central nervous system Central neurotransmission. Neuromudulation. Pathways and receptors Dialysis Dopamine Dopamine - physiology Dopamine Antagonists Excitatory amino acid Fundamental and applied biological sciences. Psychology Ibotenic Acid - administration & dosage Ibotenic Acid - analogs & derivatives Ibotenic Acid - antagonists & inhibitors Ibotenic Acid - pharmacology Injections Locomotor activity Male Methyltyrosines - pharmacology Microdialysis Motor Activity - drug effects Nucleus accumbens Nucleus Accumbens - physiology Quinoxalines - pharmacology Rats Rats, Inbred Strains Receptors, Dopamine - drug effects Receptors, Dopamine - physiology Receptors, Dopamine D1 Receptors, Dopamine D2 Stimulation, Chemical Sulpiride - pharmacology Synaptic Transmission - drug effects Tyrosine 3-Monooxygenase - antagonists & inhibitors Vertebrates: nervous system and sense organs α-Amino-3-hydroxy-5-methylisoxazole-4-proprionic acid
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