Zinc ions inhibit the protein-DNA complex formation between cyanobacterial transcription factor SmtB and its recognition DNA sequences

SmtB is a trans-acting dimeric repressor of the metal-regulated smtA gene, and the release of SmtB from the smtA operator/promoter region is essential for the tolerance to Zn2+ stress by SmtA expression. Gel retardation assaying demonstrated that different sizes of SmtB–DNA complexes were formed dep...

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Veröffentlicht in:	Plant and cell physiology 2002-10, Vol.43 (10), p.1254-1258
Hauptverfasser:	Morita, E.H. (Ehime Univ., Matsuyama (Japan). Faculty of Science), Wakamatsu, M, Uegaki, K, Yumoto, N, Kyogoku, Y, Hayashi, H
Format:	Artikel
Sprache:	eng
Schlagworte:	Abbreviation: Bbs Bacterial Proteins - genetics Bacterial Proteins - metabolism Base Sequence BINDING PROTEINS CYANOBACTERIA Cyanobacteria - genetics Cyanobacteria - metabolism Cyanophyta DNA DNA, Bacterial - metabolism DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism INHIBITION Keywords: Cyanobacteria — Heavy-metal ion sensor — Operator/promoter region — Transcription factor Molecular Sequence Data NUCLEOTIDE SEQUENCE Protein Binding - drug effects Repressor Proteins - genetics Repressor Proteins - metabolism smtA gene SmtB binding sequence SmtB gene TRANSCRIPTION FACTORS Transcription Factors - genetics Transcription Factors - metabolism ZINC Zinc - pharmacology
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