Structure, Function and Molecular Genetics of Human and Murine C1r

C1r, the enzyme responsible for intrinsic activation of the C1 complex of complement, is a modular serine protease featuring an overall structural organization homologous to those of C1s and the mannan-binding lectin-associated serine proteases (MASPs). This review will initially summarize current i...

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Veröffentlicht in:	Immunobiology (1979) 2002-09, Vol.205 (4), p.365-382
Hauptverfasser:	Arlaud, Gérard J., Gaboriaud, Christine, Garnier, Gérard, Circolo, Antonella, Thielens, Nicole M., Budayova-Spano, Monika, Fontecilla-Camps, Juan Carlos, Volanakis, John E.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Complement C1r - chemistry Complement C1r - genetics Complement C1r - physiology Complement C1s - chemistry Complement C1s - physiology Complement Pathway, Classical - physiology Enzyme Activation Humans Mice Protein Isoforms Protein Structure, Secondary Structure-Activity Relationship
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