Comparison of Solid-Phase and Solution-Phase Chiral Auxiliaries in the Alkylation/Iodolactonization Sequence to γ-Butyrolactones

Five prolinol-based chiral auxilaries have been compared for the stereoselective synthesis of γ-butyrolactones via the sequence of N-acylation, C α -allylation, and iodolactonization under both solution-phase and solid-phase conditions. Comparisons of stereoselectivity of both the C α -allylation an...

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Veröffentlicht in:	Journal of organic chemistry 2002-11, Vol.67 (22), p.7769-7773
Hauptverfasser:	Price, Michael D, Kurth, Mark J, Schore, Neil E
Format:	Artikel
Sprache:	eng
Schlagworte:	Chemistry Exact sciences and technology Heterocyclic compounds Heterocyclic compounds with o, s, se, te hetero atom and condensed derivatives Heterocyclic compounds with only one n hetero atom and condensed derivatives Organic chemistry Preparations and properties
Online-Zugang:	Volltext
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