False-positive Y-microdeletion result for a fertile male caused by an alteration under a PCR primer

Summary The pathogenic relationship between the presence of Y chromosomal microdeletions and male infertility is unclear. Nevertheless, a causal relationship is thought to be probable when loci are shown to be deleted in infertile males but are present in fertile males. Polymerase chain reaction (PC...

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Veröffentlicht in:	International journal of andrology 2002-12, Vol.25 (6), p.352-357
Hauptverfasser:	THORNHILL, A. R., GUENTHER, A. J., BARBAROTTO, G. M., SESSION, D. R., DAMARIO, M. A., DUMESIC, D. A., SNOW, K.
Format:	Artikel
Sprache:	eng
Schlagworte:	azoospermia Base Sequence Biological and medical sciences Birth control Chromosome Deletion Chromosomes, Human, Y DNA Primers - standards False Positive Reactions Fertility - genetics Gynecology. Andrology. Obstetrics Humans Infertility, Male - genetics Male male factor infertility Medical sciences microdeletions multiplex polymerase chain reaction Polymerase Chain Reaction - methods Reproducibility of Results Sterility. Assisted procreation Y chromosome
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