Humanized anti-CD154 antibody therapy for the treatment of allograft rejection in nonhuman primates

The anti-CD154 antibody hu5C8 prevents acute allograft rejection and prolongs allograft survival after withdrawal of therapy in nonhuman primates. This study describes the use of hu5C8 as a rescue agent for rejection developing after the withdrawal of hu5C8. Twelve rhesus monkeys that had received r...

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Veröffentlicht in:	Transplantation 2002-10, Vol.74 (7), p.940-943
Hauptverfasser:	HE XU, TADAKI, Douglas K, KIRK, Allan D, ELSTER, Eric A, BURKLY, Linda C, BERNING, Justin D, CRUZATA, Francis, KAMPEN, Robert L, MONTGOMERY, Sean P, PATTERSON, Noelle B, HARLAN, David M
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Animals Antibodies, Monoclonal - administration & dosage Antibodies, Monoclonal - immunology Antibodies, Monoclonal - therapeutic use Antibodies, Monoclonal, Humanized Biological and medical sciences Biopsy CD40 Ligand - immunology Chronic Disease Drug Administration Schedule Graft Rejection - drug therapy Graft Rejection - pathology Humans Immunomodulators Immunosuppression Kidney - pathology Kidney Transplantation Macaca mulatta Medical sciences Pharmacology. Drug treatments Salvage Therapy Transplantation, Homologous
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