The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10

A major gap in our knowledge of development is how the growth and identity of tissues and organs are linked during embryogenesis. The vertebrate limb is one of the best models to study these processes. Combining mutant analyses with gain- and loss-of-function approaches in zebrafish and chick embryo...

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