Expression of recombinant TGF-beta 2(442) precursor and detection in BSC-40 cells

Analysis of cDNA clones encoding transforming growth factor (TGF)-beta 2 predicts two different precursor proteins derived by alternative mRNA splicing; a 414 amino acid precursor [TGF-beta 2(414)] and a 442 amino acid precursor [TGF-beta 2(442)]. The two proteins differ by a 28 amino acid insertion...

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Veröffentlicht in:	Growth factors (Chur, Switzerland) Switzerland), 1991, Vol.5 (4), p.317-325
Hauptverfasser:	Madisen, L, Lioubin, M N, Finerty, Jr, P J, Sutter, K, Blake, J, Frederick, J, Purchio, A F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Line CHO Cells Cricetinae Immunoblotting Plasmids Protein Precursors - genetics Protein Precursors - metabolism Protein Precursors - secretion Recombinant Proteins - genetics Recombinant Proteins - metabolism Transfection Transforming Growth Factor beta - genetics Transforming Growth Factor beta - metabolism Transforming Growth Factor beta - secretion
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