Keratocyte loss in Acanthamoeba keratitis: phagocytosis, necrosis or apoptosis?

Pathogenesis of Acanthamoeba keratitis involves breakdown of epithelial barrier, stromal invasion by Acanthamoeba, loss of keratocytes, inflammatory response and finally stromal necrosis. The loss of keratocytes, believed to be due to the phagocytic activity of the parasite, occurs disproportionate...

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Veröffentlicht in:	Indian journal of ophthalmology 2000-12, Vol.48 (4), p.291-294
Hauptverfasser:	Vemuganti, G K, Sharma, S, Athmanathan, S, Garg, P
Format:	Artikel
Sprache:	eng
Schlagworte:	Acanthamoeba - isolation & purification Acanthamoeba Keratitis - parasitology Acanthamoeba Keratitis - pathology Acanthamoeba Keratitis - surgery Animals Apoptosis - genetics Corneal Stroma - parasitology Corneal Stroma - pathology Corneal Stroma - surgery DNA - analysis Eye Evisceration Humans In Situ Nick-End Labeling Keratoplasty, Penetrating Necrosis Phagocytosis - genetics
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