AVDO2 and EEG as Indicators for Treatment of Post-traumatic Brain Swelling: Experimental Study
A cat model of compression ischemia using epidural balloon inflation investigated: 1) the relationship between postischemic cerebral blood flow (CBF) and metabolism and brain swelling, 2) the use of arteriovenous oxygen difference (AVDO2) and electroencephalographic (EEG) frequency band analysis for...
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Veröffentlicht in: | Neurologia medico-chirurgica 1991, Vol.31(9), pp.568-574 |
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creator | YABUKI, Akihiko MISHINA, Hideto MIYAZAKI, Masahiro MAEDA, Minoru SATO, Kiyoshi ISHII, Shozo |
description | A cat model of compression ischemia using epidural balloon inflation investigated: 1) the relationship between postischemic cerebral blood flow (CBF) and metabolism and brain swelling, 2) the use of arteriovenous oxygen difference (AVDO2) and electroencephalographic (EEG) frequency band analysis for monitoring CBF and cerebral metabolism, and 3) indications for selecting the therapy. Global ischemia was induced by brain compression, followed by rapid decompression, and AVDO2, CBF, cerebral metabolic rate for oxygen, and EEG were monitored. The animals were divided into delayed brain swelling and no swelling groups. The severity of compression ischemia influenced the recovery of CBF and cerebral metabolism. The AVDO2 and EEG reflected the CBF and cerebral metabolism. These parameters are useful in selecting the therapy for focal brain injury. |
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Global ischemia was induced by brain compression, followed by rapid decompression, and AVDO2, CBF, cerebral metabolic rate for oxygen, and EEG were monitored. The animals were divided into delayed brain swelling and no swelling groups. The severity of compression ischemia influenced the recovery of CBF and cerebral metabolism. The AVDO2 and EEG reflected the CBF and cerebral metabolism. 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Med. Chir.(Tokyo)</addtitle><description>A cat model of compression ischemia using epidural balloon inflation investigated: 1) the relationship between postischemic cerebral blood flow (CBF) and metabolism and brain swelling, 2) the use of arteriovenous oxygen difference (AVDO2) and electroencephalographic (EEG) frequency band analysis for monitoring CBF and cerebral metabolism, and 3) indications for selecting the therapy. Global ischemia was induced by brain compression, followed by rapid decompression, and AVDO2, CBF, cerebral metabolic rate for oxygen, and EEG were monitored. The animals were divided into delayed brain swelling and no swelling groups. The severity of compression ischemia influenced the recovery of CBF and cerebral metabolism. The AVDO2 and EEG reflected the CBF and cerebral metabolism. These parameters are useful in selecting the therapy for focal brain injury.</description><subject>Animals</subject><subject>Brain Damage, Chronic - diagnosis</subject><subject>Brain Edema - blood</subject><subject>Brain Edema - diagnosis</subject><subject>Brain Edema - etiology</subject><subject>Brain Edema - physiopathology</subject><subject>Brain Edema - therapy</subject><subject>Brain Injuries - complications</subject><subject>Brain Ischemia - etiology</subject><subject>Brain Ischemia - physiopathology</subject><subject>brain swelling</subject><subject>Cats</subject><subject>cerebral blood flow</subject><subject>cerebral metabolism</subject><subject>Cerebrovascular Circulation</subject><subject>Combined Modality Therapy</subject><subject>Craniotomy</subject><subject>Diuretics - therapeutic use</subject><subject>Electroencephalography</subject><subject>Femoral Artery</subject><subject>focal brain injury</subject><subject>Intracranial Pressure</subject><subject>Jugular Veins</subject><subject>Oxygen - blood</subject><issn>0470-8105</issn><issn>1349-8029</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM9PwjAYhhujQYJcvJv05MFk2B9b2x0RETEkmIhem677hjNsw7bE-N9bAsHL18P79vm-PAhdUzJiVIr7trEjTkeZUGeoT3maJ4qw_Bz1SSpJoijJLtHQ-7oghKUq5Ur2UI9KxqkkffQy_nhcMmzaEk-nM2w8nrdlbU3onMdV5_DKgQkNtAF3FX7tfEiCM7vGhNriB2fqFr_9wGZTt-srdFGZjYfh8R2g96fpavKcLJaz-WS8SGxcGRJeMkshVaWoKhGPEhZSU0qaikIxVpCiYhWnWc6FAakUUSZ-UJwqCaBKyPgA3R64W9d978AH3dTexhtMC93Oa8kEyQQjsXh3KFrXee-g0ltXN8b9akr03p2O7jSnOrqL5ZsjdVc0UP5XD6ZiPjnkXz6YNZxy46KJDexRNM_yPe44IvWU2k_jNLT8D6EVgC4</recordid><startdate>1991</startdate><enddate>1991</enddate><creator>YABUKI, Akihiko</creator><creator>MISHINA, Hideto</creator><creator>MIYAZAKI, Masahiro</creator><creator>MAEDA, Minoru</creator><creator>SATO, Kiyoshi</creator><creator>ISHII, Shozo</creator><general>The Japan Neurosurgical Society</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1991</creationdate><title>AVDO2 and EEG as Indicators for Treatment of Post-traumatic Brain Swelling</title><author>YABUKI, Akihiko ; MISHINA, Hideto ; MIYAZAKI, Masahiro ; MAEDA, Minoru ; SATO, Kiyoshi ; ISHII, Shozo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c317t-3d2c1e48d6ff6b006ce4ad7146b822b0bf2f315936ae78808ad2c83187ee8de53</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Animals</topic><topic>Brain Damage, Chronic - diagnosis</topic><topic>Brain Edema - blood</topic><topic>Brain Edema - diagnosis</topic><topic>Brain Edema - etiology</topic><topic>Brain Edema - physiopathology</topic><topic>Brain Edema - therapy</topic><topic>Brain Injuries - complications</topic><topic>Brain Ischemia - etiology</topic><topic>Brain Ischemia - physiopathology</topic><topic>brain swelling</topic><topic>Cats</topic><topic>cerebral blood flow</topic><topic>cerebral metabolism</topic><topic>Cerebrovascular Circulation</topic><topic>Combined Modality Therapy</topic><topic>Craniotomy</topic><topic>Diuretics - therapeutic use</topic><topic>Electroencephalography</topic><topic>Femoral Artery</topic><topic>focal brain injury</topic><topic>Intracranial Pressure</topic><topic>Jugular Veins</topic><topic>Oxygen - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>YABUKI, Akihiko</creatorcontrib><creatorcontrib>MISHINA, Hideto</creatorcontrib><creatorcontrib>MIYAZAKI, Masahiro</creatorcontrib><creatorcontrib>MAEDA, Minoru</creatorcontrib><creatorcontrib>SATO, Kiyoshi</creatorcontrib><creatorcontrib>ISHII, Shozo</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Neurologia medico-chirurgica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>YABUKI, Akihiko</au><au>MISHINA, Hideto</au><au>MIYAZAKI, Masahiro</au><au>MAEDA, Minoru</au><au>SATO, Kiyoshi</au><au>ISHII, Shozo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>AVDO2 and EEG as Indicators for Treatment of Post-traumatic Brain Swelling: Experimental Study</atitle><jtitle>Neurologia medico-chirurgica</jtitle><addtitle>Neurol. Med. Chir.(Tokyo)</addtitle><date>1991</date><risdate>1991</risdate><volume>31</volume><issue>9</issue><spage>568</spage><epage>574</epage><pages>568-574</pages><issn>0470-8105</issn><eissn>1349-8029</eissn><abstract>A cat model of compression ischemia using epidural balloon inflation investigated: 1) the relationship between postischemic cerebral blood flow (CBF) and metabolism and brain swelling, 2) the use of arteriovenous oxygen difference (AVDO2) and electroencephalographic (EEG) frequency band analysis for monitoring CBF and cerebral metabolism, and 3) indications for selecting the therapy. Global ischemia was induced by brain compression, followed by rapid decompression, and AVDO2, CBF, cerebral metabolic rate for oxygen, and EEG were monitored. The animals were divided into delayed brain swelling and no swelling groups. The severity of compression ischemia influenced the recovery of CBF and cerebral metabolism. The AVDO2 and EEG reflected the CBF and cerebral metabolism. 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subjects | Animals Brain Damage, Chronic - diagnosis Brain Edema - blood Brain Edema - diagnosis Brain Edema - etiology Brain Edema - physiopathology Brain Edema - therapy Brain Injuries - complications Brain Ischemia - etiology Brain Ischemia - physiopathology brain swelling Cats cerebral blood flow cerebral metabolism Cerebrovascular Circulation Combined Modality Therapy Craniotomy Diuretics - therapeutic use Electroencephalography Femoral Artery focal brain injury Intracranial Pressure Jugular Veins Oxygen - blood |
title | AVDO2 and EEG as Indicators for Treatment of Post-traumatic Brain Swelling: Experimental Study |
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