Cellular basis for dispersion of repolarization underlying reentrant arrhythmias

Substantial heterogeneity in ion channel density and expression exists in cells isolated from various regions of the heart. Cell-to-cell coupling in the intact heart, however, is expected to attenuate the functional expression of the ion channel heterogeneities. Due to limitations of conventional el...

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Veröffentlicht in:	Journal of electrocardiology 2000, Vol.33, p.23-31
Hauptverfasser:	Akar, Fadi G., Laurita, Kenneth R., Rosenbaum, David S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Action Potentials Animals Arrhythmias, Cardiac - etiology Arrhythmias, Cardiac - physiopathology Coloring Agents Dogs Electrophysiology - methods Guinea Pigs Heart - physiology Ion Channels - physiology Kinetics Myocardium - cytology Optical Mapping Optics and Photonics reentry dispersion of repolarization Torsade de Pointes Ventricular Function
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