Hidden variables: unstable Abeta chain genes encoding antigen recognition structures in tumor survivors

Novel single exon genes Abeta4-7 comprising the Abeta6 gene family have been cloned from mouse mutants surviving transplantable metastatic tumors. Their protein coding sequences are similar to H2-Ab cDNA which encodes antigen-binding molecules of antigen presenting cells (APC); their promoters and/o...

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Veröffentlicht in:	Molecular immunology 2000-12, Vol.37 (18), p.1091-1110
Hauptverfasser:	Liu, Y, McMinimy, D L, Savinov, A Y, Johnson, K A, Kremlev, S G, Chapoval, A I, Egorov, I K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigen-Presenting Cells Base Sequence Chromosome Segregation Cloning, Molecular Exons Genetic Variation Heterozygote Histocompatibility Antigens Class II - genetics Histocompatibility Testing Introns Membrane Proteins Mice Mice, Inbred Strains Mice, Mutant Strains Models, Genetic Molecular Sequence Data Mosaicism Neoplasm Metastasis - immunology Neoplasms, Experimental - immunology Neoplasms, Experimental - mortality Survivors
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