Steroid sulfatase activity in the rat ovary, cultured granulosa cells, and a granulosa cell line

Direct production of gonadal steroids from sulfated adrenal androgens may be an important alternative or complementary pathway for ovarian steroidogenesis. The conversion of sulfated adrenal androgens, present in serum at micromolar concentrations in adult women, into unconjugated androgens or estro...

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Veröffentlicht in:	The Journal of steroid biochemistry and molecular biology 2000-12, Vol.75 (4), p.245-252
Hauptverfasser:	Clemens, Jeffrey W, Kabler, Heidi L, Sarap, Jennifer L, Beyer, Amanda R, Li, Pui-Kai, Selcer, Kyle W
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Arylsulfatases - metabolism Biological and medical sciences Cell Line Cells, Cultured Dehydroepiandrosterone Sulfate - metabolism Estrone - analogs & derivatives Estrone - biosynthesis Estrone - metabolism Female Fundamental and applied biological sciences. Psychology Granulosa cell Granulosa Cells - enzymology Granulosa Cells - metabolism Hormone metabolism and regulation In Vitro Techniques Kinetics Mammalian female genital system Ovary Ovary - enzymology Ovary - metabolism Rat Rats Rats, Sprague-Dawley Steroid sulfatase Steroidogenesis Steroids - biosynthesis Steryl-Sulfatase Substrate Specificity Vertebrates: reproduction
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