Molecular analysis of overlapping chromosomal deletions in patients with Langer-Giedion syndrome

We have obtained lymphoblastoid cell lines from three patients with Langer-Giedion syndrome who have over-lapping deletions in 8q24.1. To isolate the deletion chromosomes from their normal homologs, patient cell lines were fused with hamster cells and hybrid cells were selected for retention of huma...

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