A Case Report of Siblings with Hemolytic Uremic Syndrome from Whose Stool E. coli O157: H7 was Isolated

We experienced siblings of hemolytic uremic syndrome which occurred following diarrhea and bloody stool. They were immediately treated with dipyridamole and aspirin, and recovered from hemolytic uremic syndrome in about two weeks. E. coli O157: H7 (verotoxin producing E. coli) which is recently thou...

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Veröffentlicht in:Kansenshogaku Zasshi 1991/09/20, Vol.65(9), pp.1188-1193
Hauptverfasser: ANDOU, Mitsuhiro, ITOU, Tetsuya, ICHIKAWA, Hiromi, MIZUTANI, Fumihiko, NAGAI, Miseho, KAWAKITA, Akira, SUZUKI, Yoshimi, NISHIMURA, Yutaka, KOBAYASHI, Kazuhiro
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container_end_page 1193
container_issue 9
container_start_page 1188
container_title Kansenshogaku Zasshi
container_volume 65
creator ANDOU, Mitsuhiro
ITOU, Tetsuya
ICHIKAWA, Hiromi
MIZUTANI, Fumihiko
NAGAI, Miseho
KAWAKITA, Akira
SUZUKI, Yoshimi
NISHIMURA, Yutaka
KOBAYASHI, Kazuhiro
description We experienced siblings of hemolytic uremic syndrome which occurred following diarrhea and bloody stool. They were immediately treated with dipyridamole and aspirin, and recovered from hemolytic uremic syndrome in about two weeks. E. coli O157: H7 (verotoxin producing E. coli) which is recently thought to be related to the pathogenesis of hemolytic uremic syndrome was isolated in their stool cultures on admission. As far as we know, this is the first case in Japan from which stool E. coli 0157: H7 was detected. Moreover, we reported clinical effectiveness of genomic investigation utilizing polymerase chain reaction method for verotoxin coding region in a rapid diagnosis of this bacterial infection.
doi_str_mv 10.11150/kansenshogakuzasshi1970.65.1188
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subjects Child, Preschool
E. coli O157: H7
Escherichia coli - isolation & purification
Family Health
Feces - microbiology
Female
hemolytic uremic syndrome
Hemolytic-Uremic Syndrome - microbiology
Humans
Male
verotoxin producing E. coli
title A Case Report of Siblings with Hemolytic Uremic Syndrome from Whose Stool E. coli O157: H7 was Isolated
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