Pep12p is a Multifunctional Yeast Syntaxin that Controls Entry of Biosynthetic, Endocytic and Retrograde Traffic into the Prevacuolar Compartment

Delivery of proteins to the vacuole of the yeast Saccharomyces cerevisiae requires the function of the endosomal syntaxin, Pep12p. Many vacuolar proteins, such as the soluble vacuolar hydrolase, carboxypeptidase Y (CPY), traverse the prevacuolar compartment (PVC) en route to the vacuole. Here we sho...

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Veröffentlicht in:	Traffic (Copenhagen, Denmark) Denmark), 2000-03, Vol.1 (3), p.259-269
Hauptverfasser:	Gerrard, Sonja R., Levi, Boaz P., Stevens, Tom H.
Format:	Artikel
Sprache:	eng
Schlagworte:	Carboxypeptidase C endosome endosomes Endosomes - metabolism Fungal Proteins - physiology hydrolase Membrane Fusion Membrane Proteins - metabolism Membrane Proteins - physiology Models, Biological Mutation Organelles - metabolism Pheromone receptors prevacuole Protein Transport - physiology Qa-SNARE Proteins Receptors, Cell Surface - metabolism Receptors, G-Protein-Coupled Receptors, Mating Factor Receptors, Pheromone Saccharomyces cerevisiae Saccharomyces cerevisiae - genetics Saccharomyces cerevisiae - metabolism Saccharomyces cerevisiae - ultrastructure Saccharomyces cerevisiae Proteins SNARE SNARE Proteins Syntaxin Temperature Transmembrane domains vacuole Vacuoles Vacuoles - metabolism Vesicular Transport Proteins
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