Differential susceptibility to CD95 (Apo-1/Fas) and MHC class II-induced apoptosis during murine dendritic cell development

Disappearance of antigen presenting cells (APC) from the lymph node occurs following antigen specific interactions with T cells. We have investigated the regulation of CD95 (Apo-1/Fas) induced apoptosis during murine dendritic cell (DC) development. Consistent with the moderate levels of CD95 surfac...

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Veröffentlicht in:	Cell death and differentiation 2000-10, Vol.7 (10), p.933-938
Hauptverfasser:	McLellan, A D, Terbeck, G, Mengling, T, Starling, G C, Kiener, P A, Gold, R, Bröcker, E B, Leverkus, M, Kämpgen, E
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Chloromethyl Ketones - pharmacology Animals Antigens Apoptosis Apoptosis - drug effects Apoptosis - immunology Bone marrow Bone Marrow Cells - cytology Bone Marrow Cells - immunology Bone Marrow Cells - metabolism Caspases - metabolism CD95 antigen CD95L protein Cell death Cell Differentiation - immunology Cell division Cross-Linking Reagents - metabolism Cysteine Proteinase Inhibitors - pharmacology Dendritic cells Dendritic Cells - cytology Dendritic Cells - immunology Dendritic Cells - metabolism Dermatology fas Receptor - analysis fas Receptor - metabolism Histocompatibility Antigens Class II - analysis Histocompatibility Antigens Class II - metabolism Ligands Lymphatic system Lymphocytes Mice Mice, Inbred BALB C Mice, Inbred C57BL Mitochondria - metabolism
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