Subungual malignant melanoma: clinicopathological features of 100 cases
From the files of the Scottish Melanoma Group, we have identified 100 cases of subungual malignant melanoma (melanoma arising in the nailbed), and this represents 2.8% of the total melanomas registered during the period 1979–1989. Almost equal numbers arose on the foot as on the hand, with the thumb...
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| Veröffentlicht in: | Histopathology 1991-11, Vol.19 (5), p.425-430 |
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| container_title | Histopathology |
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| creator | BLESSING, K. KERNOHAN, N.M. PARK, K.G.M. |
| description | From the files of the Scottish Melanoma Group, we have identified 100 cases of subungual malignant melanoma (melanoma arising in the nailbed), and this represents 2.8% of the total melanomas registered during the period 1979–1989. Almost equal numbers arose on the foot as on the hand, with the thumb and big toe as the commonest digit affected. More than 80% were greater than 1.5 mm, with the mean Breslow depth 4.7 mm, and 70% were Clark level IV or V. Approximately half of the cases were of acral lentiginous type. At 5‐year follow‐up (54 cases), 26 have died of melanoma, six have died of an unrelated disease, four are alive with recurrence and 18 are alive and well. Features related to clinical outcome at 3 years were Breslow depth, mitotic count and the presence of vascular invasion. |
| doi_str_mv | 10.1111/j.1365-2559.1991.tb00232.x |
| format | Article |
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Almost equal numbers arose on the foot as on the hand, with the thumb and big toe as the commonest digit affected. More than 80% were greater than 1.5 mm, with the mean Breslow depth 4.7 mm, and 70% were Clark level IV or V. Approximately half of the cases were of acral lentiginous type. At 5‐year follow‐up (54 cases), 26 have died of melanoma, six have died of an unrelated disease, four are alive with recurrence and 18 are alive and well. Features related to clinical outcome at 3 years were Breslow depth, mitotic count and the presence of vascular invasion.</description><subject>Adult</subject><subject>Aged</subject><subject>Aged, 80 and over</subject><subject>Biological and medical sciences</subject><subject>Dermatology</subject><subject>Female</subject><subject>histopathological features</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Melanoma - mortality</subject><subject>Melanoma - pathology</subject><subject>Middle Aged</subject><subject>Nail Diseases - mortality</subject><subject>Nail Diseases - pathology</subject><subject>Prognosis</subject><subject>Scotland</subject><subject>Statistics as Topic</subject><subject>subungual malignant melanoma</subject><subject>Survival Rate</subject><issn>0309-0167</issn><issn>1365-2559</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqVkE1v1DAQhi0EKkvLT0CKEOKW4I-Mve4BCW3ptqW0lbYVR2viOIuXfGzjRN3--ybKajnXlzm8z7wePYR8ZjRhw_u2SZiQEHMAnTCtWdJllHLBk90bMjtEb8mMCqpjyqR6Tz6EsKGUKcH5ETliChSdsxlZrvqsr9c9llGFpV_XWHdR5UqsmwpPI1v62ttmi93fpmzW3g5c4bDrWxeipogYpZHF4MIJeVdgGdzH_TwmD-c_7xcX8fXt8nLx4zq2QDnEAqHQoFA6kErOuUYmcy0kRZVSJTOmUsayPJWSOwtzpbQEmmfWQZraVOfimHyderdt89i70JnKB-vK4WDX9MEoDooJlQ7g6QTatgmhdYXZtr7C9tkwakaLZmNGVWZUZUaLZm_R7IblT_tf-qxy-f_VSduQf9nnGAYlRYu19eGAgWAg5Ih9n7AnX7rnVxxgLi5XKYehIJ4KfOjc7lCA7T8jlVBg_twszdWvs_PV3W9uFuIF7amcSg</recordid><startdate>199111</startdate><enddate>199111</enddate><creator>BLESSING, K.</creator><creator>KERNOHAN, N.M.</creator><creator>PARK, K.G.M.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>199111</creationdate><title>Subungual malignant melanoma: clinicopathological features of 100 cases</title><author>BLESSING, K. ; KERNOHAN, N.M. ; PARK, K.G.M.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c5025-3a5f957a6e5676829a16d9360a74076b17411bd4662ec58779650dbce544c49d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Aged, 80 and over</topic><topic>Biological and medical sciences</topic><topic>Dermatology</topic><topic>Female</topic><topic>histopathological features</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Melanoma - mortality</topic><topic>Melanoma - pathology</topic><topic>Middle Aged</topic><topic>Nail Diseases - mortality</topic><topic>Nail Diseases - pathology</topic><topic>Prognosis</topic><topic>Scotland</topic><topic>Statistics as Topic</topic><topic>subungual malignant melanoma</topic><topic>Survival Rate</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>BLESSING, K.</creatorcontrib><creatorcontrib>KERNOHAN, N.M.</creatorcontrib><creatorcontrib>PARK, K.G.M.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Histopathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>BLESSING, K.</au><au>KERNOHAN, N.M.</au><au>PARK, K.G.M.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Subungual malignant melanoma: clinicopathological features of 100 cases</atitle><jtitle>Histopathology</jtitle><addtitle>Histopathology</addtitle><date>1991-11</date><risdate>1991</risdate><volume>19</volume><issue>5</issue><spage>425</spage><epage>430</epage><pages>425-430</pages><issn>0309-0167</issn><eissn>1365-2559</eissn><abstract>From the files of the Scottish Melanoma Group, we have identified 100 cases of subungual malignant melanoma (melanoma arising in the nailbed), and this represents 2.8% of the total melanomas registered during the period 1979–1989. 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| fulltext | fulltext |
| identifier | ISSN: 0309-0167 |
| ispartof | Histopathology, 1991-11, Vol.19 (5), p.425-430 |
| issn | 0309-0167 1365-2559 |
| language | eng |
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| source | MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adult Aged Aged, 80 and over Biological and medical sciences Dermatology Female histopathological features Humans Male Medical sciences Melanoma - mortality Melanoma - pathology Middle Aged Nail Diseases - mortality Nail Diseases - pathology Prognosis Scotland Statistics as Topic subungual malignant melanoma Survival Rate |
| title | Subungual malignant melanoma: clinicopathological features of 100 cases |
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