Werner's syndrome T lymphocytes display a normal in vitro life-span

Werner's syndrome (WS) is an autosomal recessive disorder displaying many features consistent with accelerated ageing. Fibroblasts from WS patients show a distinct mutator phenotype (characterised by the production of large chromosomal deletions) and a profound reduction in proliferative capaci...

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Veröffentlicht in:	Mechanisms of ageing and development 2000-12, Vol.121 (1-3), p.139-149
Hauptverfasser:	JAMES, S. Elizabeth, FARAGHER, Richard G. A, BURKE, Julian F, SHALL, Sydney, MAYNE, Lynne V
Format:	Artikel
Sprache:	eng
Schlagworte:	Biological and medical sciences Cells, Cultured Cellular Senescence - physiology Complex syndromes Humans Medical genetics Medical sciences Reference Values T-Lymphocytes - physiology Time Factors Werner Syndrome - blood
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