Non-MHC-restricted CD4 + T lymphocytes are regulated by HLA-Cw7-mediated inhibition

Natural killer cells (NK cells) represent an important component of innate immunity with the capacity to kill many tumor and virus-infected cells. The discovery of several classes of killer cell inhibitory receptors expressed by NK cells that bind specific MHC class I ligands on target cells provide...

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Veröffentlicht in:	Human immunology 2000-12, Vol.61 (12), p.1219-1232
Hauptverfasser:	Falk, Christine S, Nößner, Elfriede, Frankenberger, Bernhard, Schendel, Dolores J
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Blocking - pharmacology Antibodies, Monoclonal - pharmacology CD3 Complex - biosynthesis CD4 Antigens - biosynthesis CD4-Positive T-Lymphocytes - immunology CD4-Positive T-Lymphocytes - metabolism Cell Line Clone Cells Cytotoxicity, Immunologic - immunology Epitopes, T-Lymphocyte - immunology HLA-C Antigens - physiology Humans Immunologic Memory Immunophenotyping Immunosuppressive Agents - pharmacology inhibitory receptor Killer Cells, Natural - immunology Killer Cells, Natural - metabolism Lymphocyte Activation Major Histocompatibility Complex - immunology MHC class I NK cells NK-like specificity Receptors, Immunologic - analysis Receptors, Immunologic - antagonists & inhibitors Receptors, Immunologic - immunology Receptors, KIR Receptors, KIR2DL3 T cells T-Lymphocyte Subsets - immunology T-Lymphocyte Subsets - metabolism
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