Therapeutic potential of ACE inhibitors for the treatment of hypertension in Type 2 diabetes

Type 2 diabetes mellitus is associated with hypertension. If untreated, hypertension has a major impact on the clinical course of Type 2 diabetes and its vascular complications. In this review, we discuss rationale for the use of ACE inhibitors (ACEI) in hypertensive Type 2 diabetic patients and com...

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Veröffentlicht in:	Expert opinion on investigational drugs 2000-11, Vol.9 (11), p.2601-2617
Hauptverfasser:	Komers, Radko, Komersova, Karla
Format:	Artikel
Sprache:	eng
Schlagworte:	ACE inhibitors angiotensin AT1 receptor blockers Angiotensin-Converting Enzyme Inhibitors - therapeutic use Animals Clinical Trials as Topic Diabetes Mellitus, Type 2 - complications diabetic nephropathy glomerular filtration rate Humans hypertension Hypertension - drug therapy Hypertension - etiology Hypertension - physiopathology microalbuminuria myocardial infarction proteinuria Renin-Angiotensin System - drug effects Renin-Angiotensin System - physiology Type 2 diabetes mellitus
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