Statistical Molecular Design of Building Blocks for Combinatorial Chemistry

The reduction of the size of a combinatorial library can be made in two ways, either base the selection on the building blocks (BB's) or base it on the full set of virtually constructed products. In this paper we have investigated the effects of applying statistical designs to BB sets compared...

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Veröffentlicht in:	Journal of Medicinal Chemistry 2000-04, Vol.43 (7), p.1320-1328
Hauptverfasser:	Linusson, Anna, Gottfries, Johan, Lindgren, Fredrik, Wold, Svante
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Biological and medical sciences Combinatorial Chemistry Techniques Drug Design General pharmacology Medical sciences Molecular Mimicry Peptides - chemistry Pharmacology. Drug treatments Physicochemical properties. Structure-activity relationships Statistics as Topic
Online-Zugang:	Volltext
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