Changes in thermonociceptive thresholds and the role of enkephalinase A in homeostasis in morphine-tolerant rat offspring

The dynamics of thermonociceptive thresholds as a marker of the state of the endogenous opioid system was studied in the offspring of morphine-tolerant rats. Significant, age-dependent increase in thermonociceptive thresholds and higher levels of enkephalinase A in structures of the endogenous antin...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2000-05, Vol.129 (5), p.474-476
Hauptverfasser:	Litvinova, S V, Aristova, V V, Shulgovskii, V V, Terebilina, N N, Panchenko, L F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Newborn Drug Tolerance Female Homeostasis Male Maternal-Fetal Exchange Morphine - pharmacology Neprilysin - physiology Pain Threshold Pregnancy Prenatal Exposure Delayed Effects Rats Rats, Wistar Rodents Temperature
Online-Zugang:	Volltext
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