Effect of exogenous ATP on cardiac activity in rats

In vivo effects of exogenous ATP on cardiac activity were studied on adult rats. Intravenous administration of ATP produced a positive chronotropic effect, but did not affect the stroke volume. This was due to activation of type II purine receptors, rather than due to the influence of ATP hydrolysis...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2000-04, Vol.129 (4), p.320-322
Hauptverfasser:	Bilalova, G A, Anikina, T A, Sitdikov, F G, Giniatullin, R A
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - pharmacology Animals Heart - drug effects Heart - physiology Heart Rate - drug effects Myocardial Contraction - drug effects Rats Rodents Stroke Volume - drug effects
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