Physico-chemical and solid-state characterization of secnidazole

Secnidazole (hydroxy-2-propyl)-1-methyl-2-nitro-5-imidazole) is an antimicrobic agent. This drug has pharmacological activity against intestinal and hepatic amebiasis, giardiasis and vaginal trichomoniasis. This paper shows the physicochemical parameters of secnidazole determined during a preformula...

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Veröffentlicht in:	Farmaco (Società chimica italiana : 1989) 2000-11, Vol.55 (11), p.700-707
Hauptverfasser:	Boza Rivera, Anailien, González Hernández, Rolando, Novoa de Armas, Héctor, Cuéllar Elizástegi, Dulce M, Valdés Losada, Mariló
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Antibacterial agents Antibiotics. Antiinfectious agents. Antiparasitic agents Antiprotozoal Agents - chemistry Biological and medical sciences Chemical Phenomena Chemistry, Physical General pharmacology Humidity Indicators and Reagents Medical sciences Metronidazole - analogs & derivatives Metronidazole - chemistry Microscopy, Electron, Scanning Particle Size Pharmacology. Drug treatments Physico-chemical characterization Porosity Preformulation Rheology Secnidazole Solubility Spectrophotometry, Ultraviolet Spectroscopy, Fourier Transform Infrared X-Ray Diffraction
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