Use of Anti-Infective Agents During Lactation: Part 1—Beta-Lactam Antibiotics, Vancomycin, Quinupristin-Dalfopristin, and Linezolid

Because many antibiotics are excreted into the breast milk, it can be difficult for a practitioner to choose an antibiotic for a lactating patient that will have minimal risks to her nursing infant. This article is the first of a three-part series discussing the use of anti-infective agents during l...

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Veröffentlicht in:Journal of human lactation 2000-11, Vol.16 (4), p.351-358
Hauptverfasser: Chin, Karen G., Mactal-Haaf, Christina, McPherson, Charles E.
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container_end_page 358
container_issue 4
container_start_page 351
container_title Journal of human lactation
container_volume 16
creator Chin, Karen G.
Mactal-Haaf, Christina
McPherson, Charles E.
description Because many antibiotics are excreted into the breast milk, it can be difficult for a practitioner to choose an antibiotic for a lactating patient that will have minimal risks to her nursing infant. This article is the first of a three-part series discussing the use of anti-infective agents during lactation. The authors review general information regarding use and common side effects of several classes of antibiotics. They also summarize information, including documented milk concentrations, milk-to-plasma ratios, and other pharmacokinetic properties, in a table that can help practitioners choose antibiotics that may be considered safe for the lactating mother.
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subjects Acetamides - pharmacokinetics
Anti-Bacterial Agents - pharmacokinetics
Anti-Infective Agents - pharmacokinetics
beta-Lactams
Drug Therapy, Combination - pharmacokinetics
Female
Humans
Lactation - drug effects
Linezolid
Milk, Human - chemistry
Mothers - education
Nursing
Oxazolidinones - pharmacokinetics
Vancomycin - pharmacokinetics
Virginiamycin - pharmacokinetics
title Use of Anti-Infective Agents During Lactation: Part 1—Beta-Lactam Antibiotics, Vancomycin, Quinupristin-Dalfopristin, and Linezolid
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