Adrenal androgen and glucocorticoid dissociation in premenopausal rheumatoid arthritis: a significant correlate or precursor to onset?

Controlled studies of adrenal steroids in premenopausal women with rheumatoid arthritis (RA) have revealed subtle and inconsistent decreases in glucocorticosteroid (GCS) function, but prominent deficiencies of adrenal androgens (AA). Such findings have suggested that hypoandrogenicity may predispose...

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Veröffentlicht in:	Zeitschrift für Rheumatologie 2000-01, Vol.59 Suppl 2 (S2), p.II/54-II61
Hauptverfasser:	Masi, A T, Aldag, J C, Chatterton, R T, Adams, R F, Kitabchi, A E
Format:	Artikel
Sprache:	eng
Schlagworte:	Adrenal Glands - physiopathology Adrenal Insufficiency - immunology Adult Androgens - blood Arthritis, Rheumatoid - immunology Dehydroepiandrosterone Sulfate - blood Female Glucocorticoids - blood Humans Hydrocortisone - blood Middle Aged Premenopause - immunology Risk Factors
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