Competition between the replication initiator DnaA and the sequestration factor SeqA for binding to the hemimethylated chromosomal origin of E. coli in vitro

Following replication initiation, the replication origin (oriC) in Escherichia coli enters a hemimethylated state at Dam methylation sites which are recognized by the SeqA protein. SeqA binds preferentially to hemimethylated GATC sequences of DNA in vitro. SeqA is essential for the synchronous initi...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Genes to cells : devoted to molecular & cellular mechanisms 2000-11, Vol.5 (11), p.873-884
Hauptverfasser:	Taghbalout, Aziz, Landoulsi, Ahmed, Kern, Renée, Yamazoe, Mitsuyoshi, Hiraga, Sota, Holland, Barry, Kohiyama, Masamichi, Malki, Abderrahim
Format:	Artikel
Sprache:	eng
Schlagworte:	AT Rich Sequence - physiology Bacterial Outer Membrane Proteins Bacterial Proteins - genetics Bacterial Proteins - metabolism Bacterial Proteins - pharmacology Binding Sites - genetics Binding, Competitive - genetics DNA Methylation - drug effects DNA Replication - drug effects DNA Replication - genetics DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism DnaA protein Escherichia coli Escherichia coli Proteins Origin Recognition Complex Plasmids - genetics Promoter Regions, Genetic - genetics Recombinant Fusion Proteins - genetics Recombinant Fusion Proteins - metabolism Regulatory Sequences, Nucleic Acid - genetics Replication Origin - genetics replication origins SeqA protein Site-Specific DNA-Methyltransferase (Adenine-Specific) - antagonists & inhibitors Transcription Factors Viral Proteins - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!