Antiestrogenic tamoxifen and toremifene increase serum leptin levels in postmenopausal breast cancer patients

Objectives: Because estrogens stimulate the synthesis and release of leptin in the adipocytes, the effect of antiestrogens on the circulating leptin levels were studied. Methods: Thirty postmenopausal patients with breast cancer were randomized to start either with tamoxifen (20 mg/day, n=15) or tor...

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Veröffentlicht in:	Maturitas 2000-05, Vol.35 (2), p.175-179
Hauptverfasser:	Marttunen, Merja B, Andersson, Sture, Hietanen, Päivi, Karonen, Sirkka-Liisa, Koistinen, Heikki A, Koivisto, Veikko A, Tiitinen, Aila, Ylikorkala, Olavi
Format:	Artikel
Sprache:	eng
Schlagworte:	Antineoplastic agents Antineoplastic Agents, Hormonal - pharmacology Antineoplastic Agents, Hormonal - therapeutic use Biological and medical sciences Breast Neoplasms - blood Breast Neoplasms - prevention & control Estrogen Receptor Modulators - pharmacology Estrogen Receptor Modulators - therapeutic use Female General aspects Humans Leptin Leptin - blood Medical sciences Middle Aged Pharmacology. Drug treatments Postmenopause Tamoxifen Tamoxifen - pharmacology Tamoxifen - therapeutic use Toremifene Toremifene - pharmacology Toremifene - therapeutic use
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