Variation in lipid levels in morbidly obese patients operated with the LAP-BAND adjustable gastric banding system: effects of different levels of weight loss
A moderate weight loss is known to improve the lipid levels in simple obesity. The extent of weight loss needed to achieve a clinically meaningful effect on lipid abnormalities in morbid obesity is little understood. We analyzed the effects of different levels of body weight loss on the lipid levels...
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| Veröffentlicht in: | Obesity surgery 2000-12, Vol.10 (6), p.569-577 |
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| creator | Busetto, L Pisent, C Rinaldi, D Longhin, P L Segato, G De Marchi, F Foletto, M Favretti, F Lise, M Enzi, G |
| description | A moderate weight loss is known to improve the lipid levels in simple obesity. The extent of weight loss needed to achieve a clinically meaningful effect on lipid abnormalities in morbid obesity is little understood. We analyzed the effects of different levels of body weight loss on the lipid levels of morbidly obese patients operated with the LAP-BAND System.
225 morbidly obese patients (172 F and 53 M) in which a complete lipid profile has been collected both before and 12-18 months after surgery were studied. The changes of the lipid profile were analyzed according to different levels of percent weight loss (%WL: 30%).
Mean weight loss was 30.7+/-15.2 kg, corresponding to a 23.1+/-9.7% reduction of body weight. A large variability in the weight loss was observed. A significant difference in the change of the lipid parameters between the group with |
| doi_str_mv | 10.1381/096089200321594192 |
| format | Article |
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225 morbidly obese patients (172 F and 53 M) in which a complete lipid profile has been collected both before and 12-18 months after surgery were studied. The changes of the lipid profile were analyzed according to different levels of percent weight loss (%WL: <10%, 10-20%, 20-30%, >30%).
Mean weight loss was 30.7+/-15.2 kg, corresponding to a 23.1+/-9.7% reduction of body weight. A large variability in the weight loss was observed. A significant difference in the change of the lipid parameters between the group with <10%WL and the group with 10-20%WL was observed for total-cholesterol (+10.0+/-17.2% vs -0.7+/-14.7%; p<0.05), for the LDL (+18.7+/-26.3% vs +3.1+/-22.9%; p<0.05), and for the triglycerides (+7.7+/-26.3% vs -21.9+/-25.4%; p<0.05). No further significant differences were found between the two groups with greater weight loss (20-30%WL and >30%WL) and the group with 10-20%WL, the only exception being the percent change in triglycerides levels, i.e. higher in the group with %WL >30 (-33.6+/-31.5% vs -21.9+/-25.4%; p<0.05).
A moderate weight loss of 10-20% of initial body weight produced the maximal effects on the lipid levels in morbid obesity.]]></description><identifier>ISSN: 0960-8923</identifier><identifier>EISSN: 1708-0428</identifier><identifier>DOI: 10.1381/096089200321594192</identifier><identifier>PMID: 11175968</identifier><language>eng</language><publisher>United States: Springer Nature B.V</publisher><subject>Adult ; Cholesterol ; Cholesterol, HDL - blood ; Cholesterol, LDL - blood ; Female ; Gastrostomy ; Humans ; Lipoproteins - blood ; Male ; Middle Aged ; Obesity ; Obesity, Morbid - blood ; Triglycerides ; Triglycerides - blood ; Weight control ; Weight Loss</subject><ispartof>Obesity surgery, 2000-12, Vol.10 (6), p.569-577</ispartof><rights>Springer 2000</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c328t-bdecb504bf7668d71c699e18ab167de6b4fbf658972cd7b6cc4b722ce61baf6c3</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27923,27924</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11175968$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Busetto, L</creatorcontrib><creatorcontrib>Pisent, C</creatorcontrib><creatorcontrib>Rinaldi, D</creatorcontrib><creatorcontrib>Longhin, P L</creatorcontrib><creatorcontrib>Segato, G</creatorcontrib><creatorcontrib>De Marchi, F</creatorcontrib><creatorcontrib>Foletto, M</creatorcontrib><creatorcontrib>Favretti, F</creatorcontrib><creatorcontrib>Lise, M</creatorcontrib><creatorcontrib>Enzi, G</creatorcontrib><title>Variation in lipid levels in morbidly obese patients operated with the LAP-BAND adjustable gastric banding system: effects of different levels of weight loss</title><title>Obesity surgery</title><addtitle>Obes Surg</addtitle><description><![CDATA[A moderate weight loss is known to improve the lipid levels in simple obesity. The extent of weight loss needed to achieve a clinically meaningful effect on lipid abnormalities in morbid obesity is little understood. We analyzed the effects of different levels of body weight loss on the lipid levels of morbidly obese patients operated with the LAP-BAND System.
225 morbidly obese patients (172 F and 53 M) in which a complete lipid profile has been collected both before and 12-18 months after surgery were studied. The changes of the lipid profile were analyzed according to different levels of percent weight loss (%WL: <10%, 10-20%, 20-30%, >30%).
Mean weight loss was 30.7+/-15.2 kg, corresponding to a 23.1+/-9.7% reduction of body weight. A large variability in the weight loss was observed. A significant difference in the change of the lipid parameters between the group with <10%WL and the group with 10-20%WL was observed for total-cholesterol (+10.0+/-17.2% vs -0.7+/-14.7%; p<0.05), for the LDL (+18.7+/-26.3% vs +3.1+/-22.9%; p<0.05), and for the triglycerides (+7.7+/-26.3% vs -21.9+/-25.4%; p<0.05). No further significant differences were found between the two groups with greater weight loss (20-30%WL and >30%WL) and the group with 10-20%WL, the only exception being the percent change in triglycerides levels, i.e. higher in the group with %WL >30 (-33.6+/-31.5% vs -21.9+/-25.4%; p<0.05).
A moderate weight loss of 10-20% of initial body weight produced the maximal effects on the lipid levels in morbid obesity.]]></description><subject>Adult</subject><subject>Cholesterol</subject><subject>Cholesterol, HDL - blood</subject><subject>Cholesterol, LDL - blood</subject><subject>Female</subject><subject>Gastrostomy</subject><subject>Humans</subject><subject>Lipoproteins - blood</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Obesity</subject><subject>Obesity, Morbid - blood</subject><subject>Triglycerides</subject><subject>Triglycerides - blood</subject><subject>Weight control</subject><subject>Weight Loss</subject><issn>0960-8923</issn><issn>1708-0428</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2000</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNplkcluFDEQhi0EIpPAC3BAFgduDba72wu3SSAEaRQ4ANeWl_KMR71huxPNw_CueJRBSORUi776q0o_Qq8oeUdrSd8TxYlUjJCa0VY1VLEnaEUFkRVpmHyKVkegKkR9hs5T2hPCKGfsOTqjlIpWcblCv3_qGHQO04jDiPswB4d7uIM-Hethiia4_oAnAwnwXEAYc8LTDFFncPg-5B3OO8Cb9bfqcn37EWu3X1LWpge81SnHYLHRowvjFqdDyjB8wOA92KOKxy6UPBbNv0tL7x7CdlcaU0ov0DOv-wQvT_EC_bj-9P3qptp8_fzlar2pbM1krowDa1rSGC84l05Qy5UCKrWhXDjgpvHG81YqwawThlvbGMGYBU6N9tzWF-jtg-4cp18LpNwNIVnoez3CtKROsJa1smkL-OY_cD8tcSy3dZJRolqhZIHYA2Rj-SGC7-YYBh0PHSXd0bnusXNl6PVJeTEDuH8jJ6vqP6d-lkk</recordid><startdate>20001201</startdate><enddate>20001201</enddate><creator>Busetto, L</creator><creator>Pisent, C</creator><creator>Rinaldi, D</creator><creator>Longhin, P L</creator><creator>Segato, G</creator><creator>De Marchi, F</creator><creator>Foletto, M</creator><creator>Favretti, F</creator><creator>Lise, M</creator><creator>Enzi, G</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8C1</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>M0S</scope><scope>M1P</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>7X8</scope></search><sort><creationdate>20001201</creationdate><title>Variation in lipid levels in morbidly obese patients operated with the LAP-BAND adjustable gastric banding system: effects of different levels of weight loss</title><author>Busetto, L ; Pisent, C ; Rinaldi, D ; Longhin, P L ; Segato, G ; De Marchi, F ; Foletto, M ; Favretti, F ; Lise, M ; Enzi, G</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c328t-bdecb504bf7668d71c699e18ab167de6b4fbf658972cd7b6cc4b722ce61baf6c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2000</creationdate><topic>Adult</topic><topic>Cholesterol</topic><topic>Cholesterol, HDL - blood</topic><topic>Cholesterol, LDL - blood</topic><topic>Female</topic><topic>Gastrostomy</topic><topic>Humans</topic><topic>Lipoproteins - blood</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Obesity</topic><topic>Obesity, Morbid - blood</topic><topic>Triglycerides</topic><topic>Triglycerides - blood</topic><topic>Weight control</topic><topic>Weight Loss</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Busetto, L</creatorcontrib><creatorcontrib>Pisent, C</creatorcontrib><creatorcontrib>Rinaldi, D</creatorcontrib><creatorcontrib>Longhin, P L</creatorcontrib><creatorcontrib>Segato, G</creatorcontrib><creatorcontrib>De Marchi, F</creatorcontrib><creatorcontrib>Foletto, M</creatorcontrib><creatorcontrib>Favretti, F</creatorcontrib><creatorcontrib>Lise, M</creatorcontrib><creatorcontrib>Enzi, G</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>MEDLINE - Academic</collection><jtitle>Obesity surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Busetto, L</au><au>Pisent, C</au><au>Rinaldi, D</au><au>Longhin, P L</au><au>Segato, G</au><au>De Marchi, F</au><au>Foletto, M</au><au>Favretti, F</au><au>Lise, M</au><au>Enzi, G</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Variation in lipid levels in morbidly obese patients operated with the LAP-BAND adjustable gastric banding system: effects of different levels of weight loss</atitle><jtitle>Obesity surgery</jtitle><addtitle>Obes Surg</addtitle><date>2000-12-01</date><risdate>2000</risdate><volume>10</volume><issue>6</issue><spage>569</spage><epage>577</epage><pages>569-577</pages><issn>0960-8923</issn><eissn>1708-0428</eissn><abstract><![CDATA[A moderate weight loss is known to improve the lipid levels in simple obesity. The extent of weight loss needed to achieve a clinically meaningful effect on lipid abnormalities in morbid obesity is little understood. We analyzed the effects of different levels of body weight loss on the lipid levels of morbidly obese patients operated with the LAP-BAND System.
225 morbidly obese patients (172 F and 53 M) in which a complete lipid profile has been collected both before and 12-18 months after surgery were studied. The changes of the lipid profile were analyzed according to different levels of percent weight loss (%WL: <10%, 10-20%, 20-30%, >30%).
Mean weight loss was 30.7+/-15.2 kg, corresponding to a 23.1+/-9.7% reduction of body weight. A large variability in the weight loss was observed. A significant difference in the change of the lipid parameters between the group with <10%WL and the group with 10-20%WL was observed for total-cholesterol (+10.0+/-17.2% vs -0.7+/-14.7%; p<0.05), for the LDL (+18.7+/-26.3% vs +3.1+/-22.9%; p<0.05), and for the triglycerides (+7.7+/-26.3% vs -21.9+/-25.4%; p<0.05). No further significant differences were found between the two groups with greater weight loss (20-30%WL and >30%WL) and the group with 10-20%WL, the only exception being the percent change in triglycerides levels, i.e. higher in the group with %WL >30 (-33.6+/-31.5% vs -21.9+/-25.4%; p<0.05).
A moderate weight loss of 10-20% of initial body weight produced the maximal effects on the lipid levels in morbid obesity.]]></abstract><cop>United States</cop><pub>Springer Nature B.V</pub><pmid>11175968</pmid><doi>10.1381/096089200321594192</doi><tpages>9</tpages></addata></record> |
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| subjects | Adult Cholesterol Cholesterol, HDL - blood Cholesterol, LDL - blood Female Gastrostomy Humans Lipoproteins - blood Male Middle Aged Obesity Obesity, Morbid - blood Triglycerides Triglycerides - blood Weight control Weight Loss |
| title | Variation in lipid levels in morbidly obese patients operated with the LAP-BAND adjustable gastric banding system: effects of different levels of weight loss |
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