Artificial and bioartificial support systems for liver failure: a Cochrane Hepato-Biliary Group Protocol

: Aims/Background: Liver support systems may bridge patients to liver transplantation or recovery from liver failure. This review is to evaluate the beneficial and harmful effects of artificial and bioartificial support systems for acute and acute‐on‐chronic liver failure. Data Sources: Randomized t...

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Veröffentlicht in:Liver (Copenhagen) 2002-10, Vol.22 (5), p.433-438
Hauptverfasser: Liu, Jianping, Kjaergard, Lise Lotte, Als-Nielsen, Bodil, Gluud, Christian
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container_end_page 438
container_issue 5
container_start_page 433
container_title Liver (Copenhagen)
container_volume 22
creator Liu, Jianping
Kjaergard, Lise Lotte
Als-Nielsen, Bodil
Gluud, Christian
description : Aims/Background: Liver support systems may bridge patients to liver transplantation or recovery from liver failure. This review is to evaluate the beneficial and harmful effects of artificial and bioartificial support systems for acute and acute‐on‐chronic liver failure. Data Sources: Randomized trials on any support system versus standard medical therapy will be included irrespective of publication status or language. Non‐randomized studies are included in explorative analyses. Trials will be identified through bibliographies, correspondence with original investigators, and electronic searches (Cochrane Hepato‐Biliary Group Controlled Trials Register, Cochrane Controlled Trials Register, MEDLINE, EMBASE, and The Chinese Biomedical Database). Methods of the review: The extracted data will include characteristics of trials, patients, interventions, and all outcome measures. Methodological quality will be assessed by the randomization, follow up, and blinding. The RevMan and STATA will be used for statistical analyses. Sources of heterogeneity and methodological quality in the assessment of the primary outcome will be explored by sensitivity analyses and meta‐regression.
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Enteral and parenteral nutrition</subject><subject>extracorporeal liver support</subject><subject>Gastroenterology - methods</subject><subject>Humans</subject><subject>hybrid devices</subject><subject>Intensive care medicine</subject><subject>life support care</subject><subject>liver failure</subject><subject>Liver Failure, Acute - therapy</subject><subject>liver transplantation</subject><subject>Liver, Artificial</subject><subject>Medical sciences</subject><subject>Sorption Detoxification - instrumentation</subject><subject>Sorption Detoxification - methods</subject><subject>systematic review</subject><subject>Tropical medicine</subject><issn>0106-9543</issn><issn>1600-0676</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2002</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkUFv2yAUx9G0qc26foWJy3az-zBg7Ek7tNGWVoq2Hdb0iAgGlYwUD-wt-fbDTdRcdwLB78977wdCmEBJgLKrTUlqgAJqUZcVQFUC4ZyVu1do9nLxGs2AQF20nNFz9DalDQCpmeBn6JxUtAUm2hl6vI6Ds0475bF66vDaBXU6SWPfhzjgtE-D2SZsQ8Te_TERW-X8GM0nrPA86Meongy-Nb0aQnHjvFNxjxcxjD3-EcMQdPDv0BurfDKXx_UC3X_98nN-Wyy_L-7m18tCs4ayorMGGGii16ozojF5GmYbayrFBXTEMsgjVEZbDVxxoNRqRggoS7SqrWjpBfp4eLeP4fdo0iC3Lmnjfe4wjEmKipO2FTyDzQHUMaQUjZV9dNvcuCQgJ8tyIyeZcpIpJ8vy2bLc5ej7Y41xvTXdKXjUmoEPR0AlrbzNerRLJ46RtmpYlbnPB-6v82b_3w3I5d1q2uV8cci7_D-7l7yKv2QtqODy4dtCzmG1Wi2rVgr6DxMjqKo</recordid><startdate>200210</startdate><enddate>200210</enddate><creator>Liu, Jianping</creator><creator>Kjaergard, Lise Lotte</creator><creator>Als-Nielsen, Bodil</creator><creator>Gluud, Christian</creator><general>Munksgaard International Publishers</general><general>Munksgaard</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200210</creationdate><title>Artificial and bioartificial support systems for liver failure: a Cochrane Hepato-Biliary Group Protocol</title><author>Liu, Jianping ; Kjaergard, Lise Lotte ; Als-Nielsen, Bodil ; Gluud, Christian</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4834-dfe040c1cbade78e6004f8fe2a570d1f406472ecfc05a5033fc4110af1ca6f793</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2002</creationdate><topic>Anesthesia. 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subjects Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
artificial liver
Biological and medical sciences
Chronic Disease
Clinical Protocols
Cochrane
Controlled Clinical Trials as Topic
Emergency and intensive care: metabolism and nutrition disorders. Enteral and parenteral nutrition
extracorporeal liver support
Gastroenterology - methods
Humans
hybrid devices
Intensive care medicine
life support care
liver failure
Liver Failure, Acute - therapy
liver transplantation
Liver, Artificial
Medical sciences
Sorption Detoxification - instrumentation
Sorption Detoxification - methods
systematic review
Tropical medicine
title Artificial and bioartificial support systems for liver failure: a Cochrane Hepato-Biliary Group Protocol
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