CSN5/Jab1 mutations affect axis formation in the Drosophila oocyte by activating a meiotic checkpoint

The COP9 signalosome (CSN) is linked to signaling pathways and ubiquitin-dependent protein degradation in yeast, plant and mammalian cells, but its roles in Drosophila development are just beginning to be understood. We show that during oogenesis CSN5/JAB1, one subunit of the CSN, is required for me...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Development (Cambridge) 2002-11, Vol.129 (21), p.5053-5064
Hauptverfasser:	Doronkin, Sergey, Djagaeva, Inna, Beckendorf, Steven K
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Body Patterning - genetics Body Patterning - physiology Cell Cycle Proteins - genetics Cell Cycle Proteins - physiology Cell Polarity - genetics Cell Polarity - physiology COP9 Signalosome Complex DNA Repair - genetics DNA Repair - physiology DNA-Binding Proteins - genetics DNA-Binding Proteins - physiology Drosophila - cytology Drosophila - genetics Drosophila - growth & development Drosophila - physiology Drosophila Proteins - genetics Drosophila Proteins - physiology Female Gene Expression Regulation, Developmental Genes, Insect Insect Proteins - genetics Insect Proteins - physiology Intracellular Signaling Peptides and Proteins Meiosis - genetics Models, Biological Multiprotein Complexes Mutation Oocytes - cytology Oogenesis - genetics Oogenesis - physiology Peptide Hydrolases Protein Serine-Threonine Kinases Proteins - genetics Proteins - physiology Signal Transduction Transcription Factors - genetics Transcription Factors - physiology Transforming Growth Factor alpha Transforming Growth Factors - genetics Transforming Growth Factors - physiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!