The specific force of single intact extensor digitorum longus and soleus mouse muscle fibers declines with aging

In the present study we measured, for the first time, the isometric specific force (SF, force normalized to cross sectional area) generated by single intact fibers from fast- (extensor digitorum longus, EDL) and slow-twitch (soleus) muscles from young adult (2-6), middle-aged (12-14) and old (20-24...

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Veröffentlicht in:	The Journal of membrane biology 2000-12, Vol.178 (3), p.175-183
Hauptverfasser:	González, E, Messi, M L, Delbono, O
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging - physiology Animals Female Isometric Contraction Kinetics Male Mice Mice, Inbred DBA Muscle Contraction Muscle Development Muscle Fibers, Fast-Twitch - chemistry Muscle Fibers, Fast-Twitch - physiology Muscle Fibers, Slow-Twitch - chemistry Muscle Fibers, Slow-Twitch - physiology Muscle, Skeletal - growth & development Muscle, Skeletal - physiology Myosin Heavy Chains - analysis Protein Isoforms - analysis Specific Pathogen-Free Organisms
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