The importance of beta blockers in the treatment of heart failure

Heart failure, the only cardiovascular disease with an increasing incidence, is associated with significant mortality and poses a considerable economic burden. Traditionally, beta blockers have been considered to be contraindicated in patients with heart failure. Recently, however, several large ran...

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Veröffentlicht in:American family physician 2000-12, Vol.62 (11), p.2453-2462
1. Verfasser: Chavey, 2nd, W E
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description Heart failure, the only cardiovascular disease with an increasing incidence, is associated with significant mortality and poses a considerable economic burden. Traditionally, beta blockers have been considered to be contraindicated in patients with heart failure. Recently, however, several large randomized, controlled mortality trials have been stopped early because of significant improvement in mortality rates in patients with heart failure who were given beta blockers in addition to angiotensin-converting enzyme inhibitors, diuretics and, sometimes, digoxin. Beta blockers should now be considered standard therapy in patients with New York Heart Association class II or class III heart failure who are hemodynamically stable, who do not have dyspnea at rest and who have no other contraindications to the use of these agents.
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subjects Adrenergic beta-Antagonists - administration & dosage
Adrenergic beta-Antagonists - therapeutic use
Bisoprolol - therapeutic use
Carbazoles - therapeutic use
Clinical trials
Contraindications
Drug Administration Schedule
Drug therapy
Enzymes
Female
Heart failure
Heart Failure - drug therapy
Heart Failure - mortality
Heart Failure - physiopathology
Humans
Male
Metoprolol - therapeutic use
Mortality
Patient Selection
Propanolamines - therapeutic use
Randomized Controlled Trials as Topic
Severity of Illness Index
title The importance of beta blockers in the treatment of heart failure
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