Factors determining the occurrence of late potentials on the signal-averaged electrocardiogram after a first myocardial infarction: A multivariate analysis
To determine the natural history of late potentials on the signal-averaged electrocardiogram (ECG), multivariate analysis was performed in 167 patients (138 men, 29 women) with a first anterior or inferior acute myocardial infarction. Seventy-four patients received thrombolytic therapy; the remainin...
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Veröffentlicht in: | Journal of the American College of Cardiology 1991-12, Vol.18 (7), p.1638-1642 |
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description | To determine the natural history of late potentials on the signal-averaged electrocardiogram (ECG), multivariate analysis was performed in 167 patients (138 men, 29 women) with a first anterior or inferior acute myocardial infarction. Seventy-four patients received thrombolytic therapy; the remaining 93 patients were treated conventionally. All patients underwent coronary angiography, left ventricular ejection fraction determination and signal-averaged ECG recording.
Eight variables thought to be correlated with the presence of late potentials were studied; that is, age, infarct location, number of diseased coronary vessels, left ventricular ejection fraction, infarct-related coronary artery patency, treatment received, delay between admission and signal-averaged recording and delay between admission and coronary angiography. Statistical analysis showed that two independent factors (coronary artery occlusion and impaired left ventricular ejection fraction) were highly correlated with the incidence of late potentials. The occurrence of late potentials was multiplied by 5 in case of an occluded infarct-related vessel and by 1.75 each time the left ventricular ejection fraction value decreased by 0.10.
This study suggests that coronary artery patency is the most important factor that decreases the rate of late potentials after a first acute myocardial infarction and it occurs independently of infarct location and left ventricular function. |
doi_str_mv | 10.1016/0735-1097(91)90496-V |
format | Article |
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Eight variables thought to be correlated with the presence of late potentials were studied; that is, age, infarct location, number of diseased coronary vessels, left ventricular ejection fraction, infarct-related coronary artery patency, treatment received, delay between admission and signal-averaged recording and delay between admission and coronary angiography. Statistical analysis showed that two independent factors (coronary artery occlusion and impaired left ventricular ejection fraction) were highly correlated with the incidence of late potentials. The occurrence of late potentials was multiplied by 5 in case of an occluded infarct-related vessel and by 1.75 each time the left ventricular ejection fraction value decreased by 0.10.
This study suggests that coronary artery patency is the most important factor that decreases the rate of late potentials after a first acute myocardial infarction and it occurs independently of infarct location and left ventricular function.</description><identifier>ISSN: 0735-1097</identifier><identifier>EISSN: 1558-3597</identifier><identifier>DOI: 10.1016/0735-1097(91)90496-V</identifier><identifier>PMID: 1960308</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Coronary Angiography ; Electrocardiography - statistics & numerical data ; Female ; Heart - physiopathology ; Humans ; Male ; Middle Aged ; Multivariate Analysis ; Myocardial Infarction - diagnosis ; Myocardial Infarction - physiopathology ; Myocardial Infarction - therapy ; Predictive Value of Tests ; Risk Factors ; Signal Processing, Computer-Assisted ; Stroke Volume ; Survival Rate ; Thrombolytic Therapy - standards ; Vascular Patency</subject><ispartof>Journal of the American College of Cardiology, 1991-12, Vol.18 (7), p.1638-1642</ispartof><rights>1991</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c403t-cb9ea448353703f4cba03c5b900a79d755b88b093c38c9083f91ebb1405f695c3</citedby><cites>FETCH-LOGICAL-c403t-cb9ea448353703f4cba03c5b900a79d755b88b093c38c9083f91ebb1405f695c3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://dx.doi.org/10.1016/0735-1097(91)90496-V$$EHTML$$P50$$Gelsevier$$Hfree_for_read</linktohtml><link.rule.ids>314,780,784,3550,27924,27925,45995</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/1960308$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>de Chillou, Christian</creatorcontrib><creatorcontrib>Sadoul, Nicolas</creatorcontrib><creatorcontrib>Briançon, Serge</creatorcontrib><creatorcontrib>Aliot, Etienne</creatorcontrib><title>Factors determining the occurrence of late potentials on the signal-averaged electrocardiogram after a first myocardial infarction: A multivariate analysis</title><title>Journal of the American College of Cardiology</title><addtitle>J Am Coll Cardiol</addtitle><description>To determine the natural history of late potentials on the signal-averaged electrocardiogram (ECG), multivariate analysis was performed in 167 patients (138 men, 29 women) with a first anterior or inferior acute myocardial infarction. Seventy-four patients received thrombolytic therapy; the remaining 93 patients were treated conventionally. All patients underwent coronary angiography, left ventricular ejection fraction determination and signal-averaged ECG recording.
Eight variables thought to be correlated with the presence of late potentials were studied; that is, age, infarct location, number of diseased coronary vessels, left ventricular ejection fraction, infarct-related coronary artery patency, treatment received, delay between admission and signal-averaged recording and delay between admission and coronary angiography. Statistical analysis showed that two independent factors (coronary artery occlusion and impaired left ventricular ejection fraction) were highly correlated with the incidence of late potentials. The occurrence of late potentials was multiplied by 5 in case of an occluded infarct-related vessel and by 1.75 each time the left ventricular ejection fraction value decreased by 0.10.
This study suggests that coronary artery patency is the most important factor that decreases the rate of late potentials after a first acute myocardial infarction and it occurs independently of infarct location and left ventricular function.</description><subject>Coronary Angiography</subject><subject>Electrocardiography - statistics & numerical data</subject><subject>Female</subject><subject>Heart - physiopathology</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Myocardial Infarction - diagnosis</subject><subject>Myocardial Infarction - physiopathology</subject><subject>Myocardial Infarction - therapy</subject><subject>Predictive Value of Tests</subject><subject>Risk Factors</subject><subject>Signal Processing, Computer-Assisted</subject><subject>Stroke Volume</subject><subject>Survival Rate</subject><subject>Thrombolytic Therapy - standards</subject><subject>Vascular Patency</subject><issn>0735-1097</issn><issn>1558-3597</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9UU1v1TAQtBCovH78A5B8QnAIXT_HScyhUlVRQKrUC_RqbZz1wyiJH7bzpPdb-LMkTVVunHalmZ3RzjD2RsBHAaK6hFqqQoCu32vxQUOpq-LhBdsIpZpCKl2_ZJtnymt2mtIvAKgaoU_YidAVSGg27M8t2hxi4h1lioMf_bjj-SfxYO0UI412Xh3vMRPfh0xj9tgnHsZHUvK7EfsCDxRxRx2nnmyOwWLsfNhFHDi6WZYjdz6mzIfjimHP_egw2uzD-Ilf82Hqsz9g9IsPzprH5NM5e-VmM7p4mmfsx-3n7zdfi7v7L99uru8KW4LMhW01YVk2UskapCttiyCtajUA1rqrlWqbpgUtrWyshkY6LahtRQnKVVpZecberbr7GH5PlLIZfLLU9zhSmJKptwq2QmxnYrkSbQwpRXJmH_2A8WgEmKUTswRulsCNFuaxE_Mwn7190p_agbp_R2sJM3614jQ_efAUTbJ-Sb7zcc7TdMH_3-AvZc6fQA</recordid><startdate>19911201</startdate><enddate>19911201</enddate><creator>de Chillou, Christian</creator><creator>Sadoul, Nicolas</creator><creator>Briançon, Serge</creator><creator>Aliot, Etienne</creator><general>Elsevier Inc</general><scope>6I.</scope><scope>AAFTH</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19911201</creationdate><title>Factors determining the occurrence of late potentials on the signal-averaged electrocardiogram after a first myocardial infarction: A multivariate analysis</title><author>de Chillou, Christian ; Sadoul, Nicolas ; Briançon, Serge ; Aliot, Etienne</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c403t-cb9ea448353703f4cba03c5b900a79d755b88b093c38c9083f91ebb1405f695c3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Coronary Angiography</topic><topic>Electrocardiography - statistics & numerical data</topic><topic>Female</topic><topic>Heart - physiopathology</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Myocardial Infarction - diagnosis</topic><topic>Myocardial Infarction - physiopathology</topic><topic>Myocardial Infarction - therapy</topic><topic>Predictive Value of Tests</topic><topic>Risk Factors</topic><topic>Signal Processing, Computer-Assisted</topic><topic>Stroke Volume</topic><topic>Survival Rate</topic><topic>Thrombolytic Therapy - standards</topic><topic>Vascular Patency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>de Chillou, Christian</creatorcontrib><creatorcontrib>Sadoul, Nicolas</creatorcontrib><creatorcontrib>Briançon, Serge</creatorcontrib><creatorcontrib>Aliot, Etienne</creatorcontrib><collection>ScienceDirect Open Access Titles</collection><collection>Elsevier:ScienceDirect:Open Access</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American College of Cardiology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>de Chillou, Christian</au><au>Sadoul, Nicolas</au><au>Briançon, Serge</au><au>Aliot, Etienne</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Factors determining the occurrence of late potentials on the signal-averaged electrocardiogram after a first myocardial infarction: A multivariate analysis</atitle><jtitle>Journal of the American College of Cardiology</jtitle><addtitle>J Am Coll Cardiol</addtitle><date>1991-12-01</date><risdate>1991</risdate><volume>18</volume><issue>7</issue><spage>1638</spage><epage>1642</epage><pages>1638-1642</pages><issn>0735-1097</issn><eissn>1558-3597</eissn><abstract>To determine the natural history of late potentials on the signal-averaged electrocardiogram (ECG), multivariate analysis was performed in 167 patients (138 men, 29 women) with a first anterior or inferior acute myocardial infarction. Seventy-four patients received thrombolytic therapy; the remaining 93 patients were treated conventionally. All patients underwent coronary angiography, left ventricular ejection fraction determination and signal-averaged ECG recording.
Eight variables thought to be correlated with the presence of late potentials were studied; that is, age, infarct location, number of diseased coronary vessels, left ventricular ejection fraction, infarct-related coronary artery patency, treatment received, delay between admission and signal-averaged recording and delay between admission and coronary angiography. Statistical analysis showed that two independent factors (coronary artery occlusion and impaired left ventricular ejection fraction) were highly correlated with the incidence of late potentials. The occurrence of late potentials was multiplied by 5 in case of an occluded infarct-related vessel and by 1.75 each time the left ventricular ejection fraction value decreased by 0.10.
This study suggests that coronary artery patency is the most important factor that decreases the rate of late potentials after a first acute myocardial infarction and it occurs independently of infarct location and left ventricular function.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>1960308</pmid><doi>10.1016/0735-1097(91)90496-V</doi><tpages>5</tpages><oa>free_for_read</oa></addata></record> |
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source | MEDLINE; Elsevier ScienceDirect Journals Complete; EZB-FREE-00999 freely available EZB journals |
subjects | Coronary Angiography Electrocardiography - statistics & numerical data Female Heart - physiopathology Humans Male Middle Aged Multivariate Analysis Myocardial Infarction - diagnosis Myocardial Infarction - physiopathology Myocardial Infarction - therapy Predictive Value of Tests Risk Factors Signal Processing, Computer-Assisted Stroke Volume Survival Rate Thrombolytic Therapy - standards Vascular Patency |
title | Factors determining the occurrence of late potentials on the signal-averaged electrocardiogram after a first myocardial infarction: A multivariate analysis |
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