Factors determining the occurrence of late potentials on the signal-averaged electrocardiogram after a first myocardial infarction: A multivariate analysis

To determine the natural history of late potentials on the signal-averaged electrocardiogram (ECG), multivariate analysis was performed in 167 patients (138 men, 29 women) with a first anterior or inferior acute myocardial infarction. Seventy-four patients received thrombolytic therapy; the remainin...

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Veröffentlicht in:Journal of the American College of Cardiology 1991-12, Vol.18 (7), p.1638-1642
Hauptverfasser: de Chillou, Christian, Sadoul, Nicolas, Briançon, Serge, Aliot, Etienne
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container_title Journal of the American College of Cardiology
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creator de Chillou, Christian
Sadoul, Nicolas
Briançon, Serge
Aliot, Etienne
description To determine the natural history of late potentials on the signal-averaged electrocardiogram (ECG), multivariate analysis was performed in 167 patients (138 men, 29 women) with a first anterior or inferior acute myocardial infarction. Seventy-four patients received thrombolytic therapy; the remaining 93 patients were treated conventionally. All patients underwent coronary angiography, left ventricular ejection fraction determination and signal-averaged ECG recording. Eight variables thought to be correlated with the presence of late potentials were studied; that is, age, infarct location, number of diseased coronary vessels, left ventricular ejection fraction, infarct-related coronary artery patency, treatment received, delay between admission and signal-averaged recording and delay between admission and coronary angiography. Statistical analysis showed that two independent factors (coronary artery occlusion and impaired left ventricular ejection fraction) were highly correlated with the incidence of late potentials. The occurrence of late potentials was multiplied by 5 in case of an occluded infarct-related vessel and by 1.75 each time the left ventricular ejection fraction value decreased by 0.10. This study suggests that coronary artery patency is the most important factor that decreases the rate of late potentials after a first acute myocardial infarction and it occurs independently of infarct location and left ventricular function.
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source MEDLINE; Elsevier ScienceDirect Journals Complete; EZB-FREE-00999 freely available EZB journals
subjects Coronary Angiography
Electrocardiography - statistics & numerical data
Female
Heart - physiopathology
Humans
Male
Middle Aged
Multivariate Analysis
Myocardial Infarction - diagnosis
Myocardial Infarction - physiopathology
Myocardial Infarction - therapy
Predictive Value of Tests
Risk Factors
Signal Processing, Computer-Assisted
Stroke Volume
Survival Rate
Thrombolytic Therapy - standards
Vascular Patency
title Factors determining the occurrence of late potentials on the signal-averaged electrocardiogram after a first myocardial infarction: A multivariate analysis
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