New Protective System Preventing Self-Mutilation of Rat Surgical Sites
ABSTRACT -The paper presents a new approach to the rat self-mutilation mechanism, and introduces an appropriate protective system. Observations revealed that rats use three main implements to damage experimental sites, i.e., their teeth, forelegs, and hind legs. Ignoring even one of these factors di...
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| Veröffentlicht in: | Journal of reconstructive microsurgery 2000-11, Vol.16 (8), p.0609-0612 |
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| container_issue | 8 |
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| container_title | Journal of reconstructive microsurgery |
| container_volume | 16 |
| creator | Macionis, Valdas |
| description | ABSTRACT
-The paper presents a new approach to the rat self-mutilation mechanism, and introduces an appropriate protective system. Observations revealed that rats use three main implements to damage experimental sites, i.e., their teeth, forelegs, and hind legs. Ignoring even one of these factors diminishes the reliability of a protective system. Commonly used rat vests sometimes fail, since free fore- and hind legs may damage the system itself or the surgical area directly. A new system was designed to avoid these problems. A splint is glued to the fur of the rat neck and chest with fast-bonding glue, to prevent flexing the neck. Then, a vest is fabricated by wrapping adhesive tape around the chest and neck. One of the forelegs is immobilized by incorporating it into the tape vest. The action of the hind legs is neutralized by taping the feet with toes flexed. Such a protective system design is more reliable than those previously proposed, since teeth, forelegs, and hind legs are all prevented from self-mutilation. In addition, the tape vest and mittens fit the rat body well, and are easy to apply. |
| doi_str_mv | 10.1055/s-2000-9378 |
| format | Article |
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-The paper presents a new approach to the rat self-mutilation mechanism, and introduces an appropriate protective system. Observations revealed that rats use three main implements to damage experimental sites, i.e., their teeth, forelegs, and hind legs. Ignoring even one of these factors diminishes the reliability of a protective system. Commonly used rat vests sometimes fail, since free fore- and hind legs may damage the system itself or the surgical area directly. A new system was designed to avoid these problems. A splint is glued to the fur of the rat neck and chest with fast-bonding glue, to prevent flexing the neck. Then, a vest is fabricated by wrapping adhesive tape around the chest and neck. One of the forelegs is immobilized by incorporating it into the tape vest. The action of the hind legs is neutralized by taping the feet with toes flexed. Such a protective system design is more reliable than those previously proposed, since teeth, forelegs, and hind legs are all prevented from self-mutilation. In addition, the tape vest and mittens fit the rat body well, and are easy to apply.</description><identifier>ISSN: 0743-684X</identifier><identifier>EISSN: 1098-8947</identifier><identifier>DOI: 10.1055/s-2000-9378</identifier><identifier>PMID: 11127283</identifier><identifier>CODEN: JRMIE2</identifier><language>eng</language><publisher>New York, NY: Thieme</publisher><subject>Animals ; Biological and medical sciences ; Immobilization ; Medical sciences ; Miscellaneous ; Models, Animal ; Rats ; Restraint, Physical ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgical Flaps</subject><ispartof>Journal of reconstructive microsurgery, 2000-11, Vol.16 (8), p.0609-0612</ispartof><rights>Copyright © 2000 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel. +1(212)584-4662.</rights><rights>2001 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c348t-66b5553c0ea34204cd931e62ed631d9ae0e3018b3550a10d34d8efb7ffe6fdc03</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-2000-9378.pdf$$EPDF$$P50$$Gthieme$$H</linktopdf><link.rule.ids>314,780,784,3017,3018,27924,27925,54559</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=824227$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/11127283$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Macionis, Valdas</creatorcontrib><title>New Protective System Preventing Self-Mutilation of Rat Surgical Sites</title><title>Journal of reconstructive microsurgery</title><addtitle>J reconstr Microsurg</addtitle><description>ABSTRACT
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-The paper presents a new approach to the rat self-mutilation mechanism, and introduces an appropriate protective system. Observations revealed that rats use three main implements to damage experimental sites, i.e., their teeth, forelegs, and hind legs. Ignoring even one of these factors diminishes the reliability of a protective system. Commonly used rat vests sometimes fail, since free fore- and hind legs may damage the system itself or the surgical area directly. A new system was designed to avoid these problems. A splint is glued to the fur of the rat neck and chest with fast-bonding glue, to prevent flexing the neck. Then, a vest is fabricated by wrapping adhesive tape around the chest and neck. One of the forelegs is immobilized by incorporating it into the tape vest. The action of the hind legs is neutralized by taping the feet with toes flexed. Such a protective system design is more reliable than those previously proposed, since teeth, forelegs, and hind legs are all prevented from self-mutilation. In addition, the tape vest and mittens fit the rat body well, and are easy to apply.</abstract><cop>New York, NY</cop><pub>Thieme</pub><pmid>11127283</pmid><doi>10.1055/s-2000-9378</doi><tpages>4</tpages></addata></record> |
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| ispartof | Journal of reconstructive microsurgery, 2000-11, Vol.16 (8), p.0609-0612 |
| issn | 0743-684X 1098-8947 |
| language | eng |
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| source | MEDLINE; Thieme Connect Journals |
| subjects | Animals Biological and medical sciences Immobilization Medical sciences Miscellaneous Models, Animal Rats Restraint, Physical Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgical Flaps |
| title | New Protective System Preventing Self-Mutilation of Rat Surgical Sites |
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