Ascorbate in the treatment of experimental transplanted melanoma

Sodium ascorbate supplementation in drinking water inhibited subcutaneous tumor growth, enhanced levodopa methy1ester (LDME) chemotherapy, and increased survival of B16 melanoma-bearing mice. Antitumor activity was greatest in mice fed diets low in tyrosine and phenylalanine (restricted diet). Ascor...

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Veröffentlicht in:	The American journal of clinical nutrition 1991-12, Vol.54 (6), p.1284S-1291S
Hauptverfasser:	Meadows, GG, Pierson, HF, Abdallah, RM
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antineoplastic agents Ascorbic acid Ascorbic Acid - blood Ascorbic Acid - pharmacology Biological and medical sciences Dehydroascorbic Acid - pharmacology diet diet therapy drug therapy Female General aspects Levodopa - analogs & derivatives Levodopa - pharmacology Lung Neoplasms - secondary Male Malondialdehyde - blood Medical sciences melanoma Melanoma, Experimental - drug therapy Melanoma, Experimental - mortality Melanoma, Experimental - pathology metastasis Mice Neoplasm Transplantation Pharmacology. Drug treatments
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