Changes of neuron-specific enolase concentration in plasma after cardiac arrest and resuscitation

The concentration of neuron-specific enolase (NSE) was measured in plasma of 18 patients after cardiac arrest and resuscitation (14 nonsurvivors and 4 survivors). In all patients, the NSE concentration was significantly higher in comparison to reference values. The highest concentration was measured...

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Veröffentlicht in:Molecular and chemical neuropathology 1991-06, Vol.14 (3), p.237-245
Hauptverfasser: DAUBERSCHMIDT, R, ZINSMEYER, J, MROCHEN, H, MEYER, M
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container_title Molecular and chemical neuropathology
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creator DAUBERSCHMIDT, R
ZINSMEYER, J
MROCHEN, H
MEYER, M
description The concentration of neuron-specific enolase (NSE) was measured in plasma of 18 patients after cardiac arrest and resuscitation (14 nonsurvivors and 4 survivors). In all patients, the NSE concentration was significantly higher in comparison to reference values. The highest concentration was measured in nonsurvivors. Time-course investigation in the first 24 h after cardiac arrest was performed in five patients. Two nonsurvivors and one survivor of the five patients showed a significant rise, and a NSE peak concentration of 42.7 micrograms/L, 13.6 micrograms/L, and 10.5 micrograms/L, respectively, was found 10-19 h after cardiac arrest.
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subjects Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Brain Ischemia - enzymology
Brain Ischemia - etiology
Cardiopulmonary Resuscitation
Heart Arrest - complications
Heart Arrest - enzymology
Humans
Intensive care medicine
Medical sciences
Phosphopyruvate Hydratase - blood
title Changes of neuron-specific enolase concentration in plasma after cardiac arrest and resuscitation
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