Changes of neuron-specific enolase concentration in plasma after cardiac arrest and resuscitation
The concentration of neuron-specific enolase (NSE) was measured in plasma of 18 patients after cardiac arrest and resuscitation (14 nonsurvivors and 4 survivors). In all patients, the NSE concentration was significantly higher in comparison to reference values. The highest concentration was measured...
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Veröffentlicht in: | Molecular and chemical neuropathology 1991-06, Vol.14 (3), p.237-245 |
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description | The concentration of neuron-specific enolase (NSE) was measured in plasma of 18 patients after cardiac arrest and resuscitation (14 nonsurvivors and 4 survivors). In all patients, the NSE concentration was significantly higher in comparison to reference values. The highest concentration was measured in nonsurvivors. Time-course investigation in the first 24 h after cardiac arrest was performed in five patients. Two nonsurvivors and one survivor of the five patients showed a significant rise, and a NSE peak concentration of 42.7 micrograms/L, 13.6 micrograms/L, and 10.5 micrograms/L, respectively, was found 10-19 h after cardiac arrest. |
doi_str_mv | 10.1007/bf03159939 |
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In all patients, the NSE concentration was significantly higher in comparison to reference values. The highest concentration was measured in nonsurvivors. Time-course investigation in the first 24 h after cardiac arrest was performed in five patients. Two nonsurvivors and one survivor of the five patients showed a significant rise, and a NSE peak concentration of 42.7 micrograms/L, 13.6 micrograms/L, and 10.5 micrograms/L, respectively, was found 10-19 h after cardiac arrest.</description><identifier>ISSN: 1044-7393</identifier><identifier>EISSN: 2168-8729</identifier><identifier>DOI: 10.1007/bf03159939</identifier><identifier>PMID: 1958265</identifier><language>eng</language><publisher>Totowa, NJ: Humana Press</publisher><subject>Anesthesia. Intensive care medicine. Transfusions. 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In all patients, the NSE concentration was significantly higher in comparison to reference values. The highest concentration was measured in nonsurvivors. Time-course investigation in the first 24 h after cardiac arrest was performed in five patients. Two nonsurvivors and one survivor of the five patients showed a significant rise, and a NSE peak concentration of 42.7 micrograms/L, 13.6 micrograms/L, and 10.5 micrograms/L, respectively, was found 10-19 h after cardiac arrest.</description><subject>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</subject><subject>Biological and medical sciences</subject><subject>Brain Ischemia - enzymology</subject><subject>Brain Ischemia - etiology</subject><subject>Cardiopulmonary Resuscitation</subject><subject>Heart Arrest - complications</subject><subject>Heart Arrest - enzymology</subject><subject>Humans</subject><subject>Intensive care medicine</subject><subject>Medical sciences</subject><subject>Phosphopyruvate Hydratase - blood</subject><issn>1044-7393</issn><issn>2168-8729</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkDtP7DAQhS0EguXR3B7JBaJACvjtuLyseElINFBHE2cMvso6e-2k4N8T2AWqGc355ujoEPKHs0vOmL1qA5NcOyfdDlkIbuqqtsLtkgVnSlVWOnlADkv5x5gRshb7ZJ87XQujFwSWb5BesdAh0IRTHlJV1uhjiJ5iGnooSP2QPKYxwxiHRGOi6_m8AgphxEw95C6Cp5AzlpFC6ui8TMXH8evhmOwF6AuebOcRebm9eV7eV49Pdw_Lv4-Vl9aOFXYSgwqgsDbCGA-s9rYVrVJQmxahE6qWxjihO9MGba3sgkLsWMu50M7II3K-8V3n4f80R2lWsXjse0g4TKWxQjlttZ3Biw3o81BKxtCsc1xBfm84az77bK5vv_uc4dOt69SusPtFNwXO-tlWh-KhDxmSj-UH07OPtEp-AMOzfi8</recordid><startdate>19910601</startdate><enddate>19910601</enddate><creator>DAUBERSCHMIDT, R</creator><creator>ZINSMEYER, J</creator><creator>MROCHEN, H</creator><creator>MEYER, M</creator><general>Humana Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19910601</creationdate><title>Changes of neuron-specific enolase concentration in plasma after cardiac arrest and resuscitation</title><author>DAUBERSCHMIDT, R ; ZINSMEYER, J ; MROCHEN, H ; MEYER, M</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c377t-ed3ef4fa4e86266ca08c7b2b44a86bead248366925d6bf5773df4eed0b1125963</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy</topic><topic>Biological and medical sciences</topic><topic>Brain Ischemia - enzymology</topic><topic>Brain Ischemia - etiology</topic><topic>Cardiopulmonary Resuscitation</topic><topic>Heart Arrest - complications</topic><topic>Heart Arrest - enzymology</topic><topic>Humans</topic><topic>Intensive care medicine</topic><topic>Medical sciences</topic><topic>Phosphopyruvate Hydratase - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>DAUBERSCHMIDT, R</creatorcontrib><creatorcontrib>ZINSMEYER, J</creatorcontrib><creatorcontrib>MROCHEN, H</creatorcontrib><creatorcontrib>MEYER, M</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Molecular and chemical neuropathology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>DAUBERSCHMIDT, R</au><au>ZINSMEYER, J</au><au>MROCHEN, H</au><au>MEYER, M</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Changes of neuron-specific enolase concentration in plasma after cardiac arrest and resuscitation</atitle><jtitle>Molecular and chemical neuropathology</jtitle><addtitle>Mol Chem Neuropathol</addtitle><date>1991-06-01</date><risdate>1991</risdate><volume>14</volume><issue>3</issue><spage>237</spage><epage>245</epage><pages>237-245</pages><issn>1044-7393</issn><eissn>2168-8729</eissn><abstract>The concentration of neuron-specific enolase (NSE) was measured in plasma of 18 patients after cardiac arrest and resuscitation (14 nonsurvivors and 4 survivors). In all patients, the NSE concentration was significantly higher in comparison to reference values. The highest concentration was measured in nonsurvivors. Time-course investigation in the first 24 h after cardiac arrest was performed in five patients. Two nonsurvivors and one survivor of the five patients showed a significant rise, and a NSE peak concentration of 42.7 micrograms/L, 13.6 micrograms/L, and 10.5 micrograms/L, respectively, was found 10-19 h after cardiac arrest.</abstract><cop>Totowa, NJ</cop><pub>Humana Press</pub><pmid>1958265</pmid><doi>10.1007/bf03159939</doi><tpages>9</tpages></addata></record> |
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subjects | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Brain Ischemia - enzymology Brain Ischemia - etiology Cardiopulmonary Resuscitation Heart Arrest - complications Heart Arrest - enzymology Humans Intensive care medicine Medical sciences Phosphopyruvate Hydratase - blood |
title | Changes of neuron-specific enolase concentration in plasma after cardiac arrest and resuscitation |
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