Recruitment of patients to a glaucoma drug trial in a district general hospital
We report the difficulties experienced in identifying and recruiting 21 patients with ocular hypertension or primary open-angle galucoma to participate in a clinical trial of two topical beta-blockers. The case-notes of 374 consecutive patients expected to attend routine glaucoma clinics were review...
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| Veröffentlicht in: | Eye (London) 1991, Vol.5 (3), p.329-332 |
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| container_end_page | 332 |
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| container_title | Eye (London) |
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| creator | Sunderraj, Palaniswamy Peiris, Colin S L |
| description | We report the difficulties experienced in identifying and recruiting 21 patients with ocular hypertension or primary open-angle galucoma to participate in a clinical trial of two topical beta-blockers. The case-notes of 374 consecutive patients expected to attend routine glaucoma clinics were reviewed to recruit 21 eligible patients who were willing to undergo the drug trial. Recruitment of patients to prospective drug trials may be complicated by a high proportion of exclusions due to ineligibility and also by refusal of otherwise eligible patients. |
| doi_str_mv | 10.1038/eye.1991.52 |
| format | Article |
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The case-notes of 374 consecutive patients expected to attend routine glaucoma clinics were reviewed to recruit 21 eligible patients who were willing to undergo the drug trial. Recruitment of patients to prospective drug trials may be complicated by a high proportion of exclusions due to ineligibility and also by refusal of otherwise eligible patients.</description><subject>Adrenergic beta-Antagonists - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Clinical Trials as Topic</subject><subject>Glaucoma and intraocular pressure</subject><subject>Glaucoma, Open-Angle - drug therapy</subject><subject>Hospitals, District</subject><subject>Hospitals, General</subject><subject>Humans</subject><subject>Informed Consent</subject><subject>Laboratory Medicine</subject><subject>Medical Records</subject><subject>Medical sciences</subject><subject>Medicine</subject><subject>Medicine & Public Health</subject><subject>Ocular Hypertension - drug therapy</subject><subject>Ophthalmology</subject><subject>Patient Compliance</subject><subject>Patients</subject><subject>Pharmaceutical Sciences/Technology</subject><subject>Prospective Studies</subject><subject>Surgery</subject><subject>Surgical Oncology</subject><subject>United Kingdom</subject><issn>0950-222X</issn><issn>1476-5454</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1991</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNptkMtLAzEQh4MotVZPnoVc9KJbk2z2kaMUX1AoiIK3MM1Oaso-arJ76H9vSgu9eJrH72MGPkKuOZtylpaPuMUpV4pPM3FCxlwWeZLJTJ6SMVMZS4QQ3-fkIoQ1YzEs2IiMeF6mQskxWXyg8YPrG2x72lm6gd7FNtC-o0BXNQyma4BWfljR3juoqWtjULkQJ9PTFbbo4_anCxvXQ31JzizUAa8OdUK-Xp4_Z2_JfPH6PnuaJyZlqUi4BOSZyEtl8sJUouQ5ciPRKlZWmZK5yA0WYKHKDcNUWoA4Lq0pLLKl4umE3O3vbnz3O2DodeOCwbqGFrsh6EJIxVmxA-_3oPFdCB6t3njXgN9qzvROn4769E6fzkSkbw5nh2WD1ZHd-4r57SGHYKC2HlrjwhFTRSrScvf1Yc-FGLUr9HrdDb6NRv59-wd13YeH</recordid><startdate>1991</startdate><enddate>1991</enddate><creator>Sunderraj, Palaniswamy</creator><creator>Peiris, Colin S L</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>1991</creationdate><title>Recruitment of patients to a glaucoma drug trial in a district general hospital</title><author>Sunderraj, Palaniswamy ; Peiris, Colin S L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3032-14ae152689c67cd2816e1c4ef908d594626ce7afad6c0e34faae7abfc7fe0b913</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1991</creationdate><topic>Adrenergic beta-Antagonists - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Clinical Trials as Topic</topic><topic>Glaucoma and intraocular pressure</topic><topic>Glaucoma, Open-Angle - drug therapy</topic><topic>Hospitals, District</topic><topic>Hospitals, General</topic><topic>Humans</topic><topic>Informed Consent</topic><topic>Laboratory Medicine</topic><topic>Medical Records</topic><topic>Medical sciences</topic><topic>Medicine</topic><topic>Medicine & Public Health</topic><topic>Ocular Hypertension - drug therapy</topic><topic>Ophthalmology</topic><topic>Patient Compliance</topic><topic>Patients</topic><topic>Pharmaceutical Sciences/Technology</topic><topic>Prospective Studies</topic><topic>Surgery</topic><topic>Surgical Oncology</topic><topic>United Kingdom</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Sunderraj, Palaniswamy</creatorcontrib><creatorcontrib>Peiris, Colin S L</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Eye (London)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Sunderraj, Palaniswamy</au><au>Peiris, Colin S L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Recruitment of patients to a glaucoma drug trial in a district general hospital</atitle><jtitle>Eye (London)</jtitle><stitle>Eye</stitle><addtitle>Eye (Lond)</addtitle><date>1991</date><risdate>1991</risdate><volume>5</volume><issue>3</issue><spage>329</spage><epage>332</epage><pages>329-332</pages><issn>0950-222X</issn><eissn>1476-5454</eissn><coden>EYEEEC</coden><abstract>We report the difficulties experienced in identifying and recruiting 21 patients with ocular hypertension or primary open-angle galucoma to participate in a clinical trial of two topical beta-blockers. 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| fulltext | fulltext |
| identifier | ISSN: 0950-222X |
| ispartof | Eye (London), 1991, Vol.5 (3), p.329-332 |
| issn | 0950-222X 1476-5454 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_72491071 |
| source | MEDLINE; Springer journals; EZB Electronic Journals Library |
| subjects | Adrenergic beta-Antagonists - therapeutic use Biological and medical sciences Clinical Trials as Topic Glaucoma and intraocular pressure Glaucoma, Open-Angle - drug therapy Hospitals, District Hospitals, General Humans Informed Consent Laboratory Medicine Medical Records Medical sciences Medicine Medicine & Public Health Ocular Hypertension - drug therapy Ophthalmology Patient Compliance Patients Pharmaceutical Sciences/Technology Prospective Studies Surgery Surgical Oncology United Kingdom |
| title | Recruitment of patients to a glaucoma drug trial in a district general hospital |
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